Results 91 to 100 of about 5,909,792 (272)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The study of composition at the post-secondary level is a relatively new practice which has become widespread only during the past half-century. More recent is the emergence over the past two to three decades of composition studies as an academic ...
Madeleine Youmans
doaj
Syntactic Interference of the Indonesian Language in Intermediate-Level German Composition
This study examines the phenomenon of syntactic interference arising from the structural differences between Indonesian (L1) and German (L2) in compositions written by B1-level students.
Rount Maulero, Hayatul Cholsy
doaj +1 more source
Insights into Low-Resource Language Modelling: Improving Model Performances for South African Languages [PDF]
To address the gap in natural language processing for Southern African languages, our paper presents an in-depth analysis of language model development under resource-constrained conditions.
Ruan Visser +2 more
doaj +3 more sources
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The Collision of Two Lexicons: Librarians, Composition Instructors and the Vocabulary of
Objective – The study has two aims. The first is to identify words and phrases from information literacy and rhetoric and composition that students used to justify the comparability of two sources. The second is to interpret the effectiveness of students’
Toni M. Carter, Toni M. Carter
doaj
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source

