Results 71 to 80 of about 1,318,721 (297)

Composition of Motion Description Languages [PDF]

open access: yes, 2008
We introduce a new formalism to compose interacting heterogeneous systems described by extended motion description languages ( mdl es). The novelty lies in producing a composed system whose behavior could be a superset of the union of the behaviors of its generators. In the class of systems modeled using mdl es, the composition operator is closed, and
Wenqi Zhang, Herbert G. Tanner
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Visões da língua(gem) em comentários sobre internetês não é língua portuguesa

open access: yesFilologia e Linguística Portuguesa, 2006
This paper aims to discuss the representation that university students of letters and pedagogy courses use in the so-called “internetês”, a grapholinguistic form which has been spread in digital genres such as chats, blogs and social networks as the ...
Fabiana Komesu
doaj   +1 more source

ICL: The Image Composition Language [PDF]

open access: yes
The Image Composition Language (ICL) provides a convenient way for programmers of interactive graphics application programs to define how the video look-up table of a raster display system is to be loaded.
Foley, James D., Kim, Won Chul
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

PECULIARITIES OF THE MUSICAL LANGUAGE, COMPOSITION AND DRAMATURGY IN S. PISLARI’S COMPOSITION LES CANTILÈNES FOR PIANO [PDF]

open access: yesStudiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2017
The author of the given article analyzes the piano work by Snejana Pislari «Les Cantilènes», considered from the aspect of content and form. The conclusion is made that the musical language and the specifics of the composition and dramaturgy of this work
CABACOV DMITRII, ŢIRCUNOVA SVETLANA
doaj  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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