Results 71 to 80 of about 209,516 (359)

Atomic service-based scheduling for web services composition [PDF]

open access: yes, 2006
With the rapid development of Internet technologies and widespread of Internet applications, Web Services has become an important research issue of World Wide Web Consortium (W3C).
Han, Shukang
core  

TumorML: Concept and requirements of an in silico cancer modelling markup language [PDF]

open access: yes, 2011
This paper describes the initial groundwork carried out as part of the European Commission funded Transatlantic Tumor Model Repositories project, to develop a new markup language for computational cancer modelling, TumorML.
Cooper, Jonathan   +5 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Visões da língua(gem) em comentários sobre internetês não é língua portuguesa

open access: yesFilologia e Linguística Portuguesa, 2006
This paper aims to discuss the representation that university students of letters and pedagogy courses use in the so-called “internetês”, a grapholinguistic form which has been spread in digital genres such as chats, blogs and social networks as the ...
Fabiana Komesu
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

PECULIARITIES OF THE MUSICAL LANGUAGE, COMPOSITION AND DRAMATURGY IN S. PISLARI’S COMPOSITION LES CANTILÈNES FOR PIANO [PDF]

open access: yesStudiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2017
The author of the given article analyzes the piano work by Snejana Pislari «Les Cantilènes», considered from the aspect of content and form. The conclusion is made that the musical language and the specifics of the composition and dramaturgy of this work
CABACOV DMITRII, ŢIRCUNOVA SVETLANA
doaj  

A Framework for Design and Composition of Semantic Web Services

open access: yes, 2004
Semantic Web Services (SWS) are Web Services (WS) whose description is semantically enhanced with markup languages (e.g., OWL-S). This semantic description will enable external agents and programs to discover, compose and invoke SWSs.
Manuel Lama   +5 more
core  

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