Results 61 to 70 of about 18,935,031 (298)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Augmenting Clinical Insights with Computing: How TalkBank has Impacted Assessment and Treatment of Speech and Language Disorders [PDF]
Our purpose is to highlight the contributions of TalkBank initiatives to improved understanding of clinical impairments in adult and child speakers and examine remaining challenges and proposed solutions.We review the origins and development of TalkBank ...
Nan Bernstein Ratner
core +1 more source
Jornal de Pediatria (Versão em Português), 2015 Objective: To review the literature that addresses the relationship between prematurity, birth weight, and development of language in Brazilian children.
Amanda B. Zerbeto +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
DiagnosticsBackground/Objectives: Developmental Language Disorder (DLD) is a persistent neurodevelopmental condition with an estimated prevalence of 7% in preschoolers.
Diego Lourenço dos Santos Silva +4 more
doaj +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Literacy and comprehension in school-aged children: Studies on autism and other developmental disabilities [PDF]
, 2008 The present thesis consists of five studies and addresses literacy and comprehension skills in children with autism spectrum disorders (ASD, including Asperger’s disorder) and, to a lesser extent, attention disorders (eg. Attention Deficits Hyperactivity
Åsberg, Jakob +3 more
core +1 more source
Infantile epileptic spasms syndrome caused by TBL1XR1 gene variation: three cases report
Chinese Journal of Contemporary Neurology and NeurosurgeryObjective To summarize the clinical characteristics, genotypes and prognosis of infantile epileptic spasms syndrome (IESS) caused by TBL1XR1 gene variation.
LÜ Qiu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source