Results 61 to 70 of about 848,161 (308)

Screening for developmental disorders in 3- and 4-year-old italian children: a preliminary study [PDF]

open access: yes, 2017
BACKGROUND: The "Osserviamo" project, coordinated by the Municipality of Rome and the Department of Pediatrics and Child Neuropsychiatry of Sapienza University, aimed to validate an Italian version of the Ages and Stages Questionnaire-3 and to collect ...
Catino, E   +8 more
core   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Pengaruh Pemberian Asi Eksklusif Dan Tingkat Pendidikan Orang Tua Terhadap Perkembangan Bicara Dan Bahasa Pada Anak Usia 3-5 Tahun Di Kelurahan Makam Haji Kecamatan Kartasura Kabupaten Sukoharjo [PDF]

open access: yes, 2018
Some data indicate the incidence of children with speech delay is quite high. Communication disorders and cognitive impairment are part of a child development disorders, occuring in about 8%.
, dr. N Juni Triastuti, M.Med. Ed.   +1 more
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Developmental disorders [PDF]

open access: yes, 2002
Introduction: Connectionist models have recently provided a concrete computational platform from which to explore how different initial constraints in the cognitive system can interact with an environment to generate the behaviors we find in normal ...
Karmiloff-Smith, Annette   +1 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Development of Print Awareness in Language-Disordered Preschoolers

open access: yesJournal of Speech, Language, and Hearing Research, 1985
This study examined print awareness and related oral language abilities in language-disordered and normally developing preschoolers. Twenty subjects, ages 3:1 to 6:5 (years:months), were shown high frequency environmental print in four conditions varying in the amount of non-print information present in the print setting.
Gillam, Ronald B., Johnston, J.
openaire   +3 more sources

Neurokognitív integrációs folyamatok, nyelvfejlődés és nyelvi zavarok = Neurocognitive integration processes, language development and language disorders [PDF]

open access: yes, 2008
A pályázatban olyan integrációs folyamatokat vizsgáltuk, amelyeknek szerepe a nyelvi feldolgozásban kevésbé ismert. Elektrofiziológiai módszerekkel megállapítottuk, hogy a szóhangsúly feldolgozását az akusztikai tulajdonságok, és a hangsúlymintázat ...
Csépe, Valéria   +3 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Association between gestational age and birth weight on the language development of Brazilian children: a systematic review

open access: yesJornal de Pediatria (Versão em Português), 2015
Objective: To review the literature that addresses the relationship between prematurity, birth weight, and development of language in Brazilian children.
Amanda B. Zerbeto   +2 more
doaj   +1 more source

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