Results 241 to 250 of about 895,253 (348)

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

The Role of Large Language Models in Ophthalmology: A Review of Current Applications, Performance, and Future Directions. [PDF]

Cureus
Cohen L, Gupta AR, Patel P, Gill GS, Bains H, Gupta S.   +5 more
europepmc   +1 more source

Ethnographically Informed Language Documentation [PDF]

, 2005
Harrison, K. David
core   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Large Language Model–Based Assessment of Clinical Reasoning Documentation in the Electronic Health Record Across Two Institutions: Development and Validation Study

Verity Schaye, David J DiTullio, Benedict Guzman, Scott Vennemeyer, Hanniel Shih, Ilan Reinstein, Danielle Weber, Abbie Goodman, Danny T Y Wu, Daniel J. Sartori, Sally A. Santen, Larry D. Gruppen, Yindalon Aphinyanaphongs, Jesse Burk‐Rafel   +13 more
openalex   +1 more source

MCP-enabled LLM for meta-optics inverse design: leveraging differentiable solver without LLM expertise. [PDF]

Nanophotonics
Huang Y, Zheng B, Dong Y, Tang H, Zhao H, Shawon RH, An S, Zhang H.   +7 more
europepmc   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Commentary: Design science research as a pathway to strengthening evidence within the nursing intervention classification. [PDF]

J Res Nurs
White M.
europepmc   +1 more source

Brazilian Sign Language documentation

, 2020
Ronice Müller de Quadros, Tarcísio de Arantes Leite, Juliana Tasca Lohn, Deonísio Schmitt, Carolina Pego   +4 more
openaire   +1 more source