Results 61 to 70 of about 5,938,811 (248)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Table of Contents, 2(1)

, 2008
Table of Contents for the June 2008 issue (Volume 2, Number 1) of Language Documentation & Conservation.National Foreign Language Resource ...
Language Documentation & Conservation
core   +1 more source

Archival analog drawings for semantic segmentation of Roman Architectural Heritage using Deep Learning [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The present study aims to investigate whether the graphic code embedded in analogue architectural drawings—characterised by standardised textures and conventions—provides sufficient semantic information to support a simple, robust, and ...
M. B. Trivi
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

From Static Preservation to Dynamic Continuity: The Historical Evolution of Architectural Heritage Restoration Methods

Information
Architectural heritage restoration has expanded rapidly, yet its knowledge base remains fragmented across materials, structural assessment, digital technologies, and conservation management.
Yuhan Zhang, Yansheng Wang
doaj   +1 more source

Linguistic and metalinguistic training to support use of audio 'chunks' in language revitalisation

, 2019
Archival audio documentation can play an important role in language revitalisation contexts with few or no fluent speakers. However this data must be made available in a form that meets the needs of language teachers and learners. This paper suggests one
Merlan, Francesca, Lee, Chweebeng (R17032), MacRitchie, Jennifer (R17955), Richards, Mark B. (R20004), Lardy, Josephine, Jones, Caroline (R8989)   +5 more
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Editorial Board, 2(2)

, 2008
Editorial Board for the December 2008 issue (Volume 2, Number 2) of Language Documentation & Conservation.National Foreign Language Resource ...
Language Documentation & Conservation
core   +1 more source

Knowledge Structure and Evolution of Industrial Heritage Digitalization: A Comparative Bibliometric Analysis Using CiteSpace and AI-Assisted Methods

Buildings
Industrial heritage digitalization increasingly connects documentation, conservation, adaptive reuse, regeneration, and heritage management, yet its interdisciplinary terminology complicates systematic characterization of the field.
Feng Wang, Haoyu Yang, Yuting Yin, Zilin Zhou   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source