Results 71 to 80 of about 5,938,811 (248)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

The Documentation of Chedungun and the Pewenche Highlands: Phase One [PDF]

open access: yes
This article provides a descriptive guide to the documentation of Chedungun, the regional variant of Mapudungun (ISO 639-2 code arn) that is spoken by the Pewenche people.
Vita-Manquepi, Sonia   +1 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Artificial intelligence in immovable cultural heritage research: a bibliometric and knowledge mapping review

open access: yesBuilt Heritage
In recent years, the application of artificial intelligence (AI) in immovable cultural heritage research has expanded rapidly, supporting new approaches to heritage documentation, condition assessment, conservation, management, and public communication ...
Yangting Wen, Marzudi Md Yunus
doaj   +1 more source

4th International Conference on Language Documentation & Conservation (ICLDC) evaluation report [PDF]

open access: yes, 2015
This document reports on, and evaluates the 4th International Conference on Language Documentation & Conservation (ICLDC) held at the University of Hawai‘i, Mānoa, from February 26–March 1, 2015.This document reports on, and evaluates the 4th ...
Berez-Kroeker, Andrea, Yoshioka, Jim
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Makna Leksikon Budidaya Tambak sebagai Representasi Kearifan Lokal dan Harmoni Ekologis Masyarakat Desa Wedani, Gresik: Kajian Antropolinguistik

open access: yesKajian Linguistik dan Sastra
The community of Gresik, particularly in Desa Wedani, has a rich lexicon related to fish pond cultivation. This study aims to: (1) describe the morphological formation process of fish farming lexicon in the local community; (2) analyze the structure and ...
Kharisma Shinta, Millatuz Zakiyah
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Propuesta de un archivo virtual dinámico en PHP para gestionar la documentación electoral manuscrita del Archivo Histórico del Congreso de los Diputados de España

open access: yesDocumentación de las Ciencias de la Información, 2007
The programming language PHP is a mixture of different programming languages. Mainly, it uses the syntax that most of the programmers knows of the programming language C, but is very different from this last one, since PHP is an interpreted programming ...
Nadia Villarejo Sánchez
doaj  

Ontology-Based Digital Preservation Framework for Phum Riang Silk Heritage

open access: yesInformatics
Traditional textile crafts face significant challenges in preserving and transferring knowledge due to the aging of expert artisans and declining community engagement.
A-Phorn Molee   +3 more
doaj   +1 more source

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