Results 51 to 60 of about 4,743,118 (286)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Exploring Family Language Policy: Parental Perspectives in Homshetsma-Speaking Families

Dilbilim Araştırmaları Dergisi
The preservation of heritage languages often relies on family language policies (FLP), shaped by parental attitudes and practices (Fishman, 1991). This study investigates FLP in Homshetsma-speaking families, focusing on the endangered status of the ...
Gülay AKIN
doaj   +1 more source

Coptic Language Learning and Social Media

Languages, 2019
This study explored the potential of using the Internet, including existing social media platforms, for Coptic language learning. Through global exposure, endangered language maintenance and revitalization efforts may benefit from having a presence on ...
D. Nicole Deschene
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Interpreting language-learning data [PDF]

, 2020
This book provides a forum for methodological discussions emanating from researchers engaged in studying how individuals acquire an additional language.
Gudmestad, Aarnes; Virginia Polytechnic Institute and State University, Huang, Xiaoliang; Beijing Foreign Studies University, Leclercq, Pascale; Université Paul Valéry Montpellier 3, Trévisiol, Pascale; Université Paris 3 & DILTEC EA 2288, Watorek, Marzena; Université Paris 8 & UMR-SFL, CNRS, Scheuer, Sylwia; University of Paris 3 – Sorbonne Nouvelle, Horgues, Céline; University of Paris 3 – Sorbonne Nouvelle, Majdoub, Hedi; Université Paris 8 & UMR-SFL, CNRS, Yu, Xinyue Cécilia; Inalco - CNRS - EHESS, CRLAO, Pélissier, Maud; University of Agder, Rast, Rebekah; American University of Paris & UMR-SFL, CNRS, Søfteland, Åshild; Østfold University College, Guan, Qianwen; City University of Hong Kong, Emilsen, Linda Evenstad; Østfold University College, Hilton, Heather E.; Université Lumière Lyon 2, Edmonds, Amanda, Leclercq, Pascale, Osborne, John; Université Savoie Mont Blanc, Gudmestad, Aarnes   +18 more
core   +1 more source

Exploring the Severity of First Language Attrition among the Private University Students of Bangladesh

Dialogica
This article examines the severity of first language attrition among private university students in Bangladesh, with particular attention to the attrition of Bangla in English-dominant academic environments.
Sifat Shahriar Bhuiyan
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Third language acquisition: Age, proficiency and multilingualism [PDF]

, 2020
This book deals with the phenomenon of third language (L3) acquisition. As a research field, L3 acquisition is established as a branch of multilingualism that is concerned with how multilinguals learn additional languages and the role that their ...
Gudmundson, Anna, Sleeman, Petra, Sánchez, Laura, Sciutti, Sandro, Bardel, Camilla, Salaberry, Rafael, Muñoz, Carmen, Stadt, Rosalinde, Pfenninger, Simone E., Hulk, Aafke   +9 more
core   +1 more source

Euskararen belaunez beluneko jarraipena eta hizkuntza sozializazioa Nafarroako familia euskaldunetan (1970-2012) [PDF]

Fontes Linguae Vasconum, 2013
Artikulu honetan Nafarroako historia hurbilean (hondar lau hamarkadetan, 1970etik 2012ra) euskararen belaunez belauneko jarraipena nola gauzatu den eta egungo haur nafarrak zer egoeratan bilakatzen diren euskaldun aztertu da.
Paula Kasares
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source