Results 61 to 70 of about 12,926,992 (276)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Measuring Motivation: A Statistical Lens on Gender Differences in Online Reading Activities [PDF]
SHS Web of ConferencesWhen it comes to online reading activities, every student has a different motivation to read, particularly male and female students. The purpose of this study was to test the hypothesis (H1) saying that there is a significant difference between male and ...
Puspitasari Evi +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The Applicability of Spolsky’s Tripartite Model in Three Contexts
Darnioji daugiakalbystėThis study evaluates the applicability of Spolsky’s tripartite model of language policy, consisting of language beliefs, practices, and management across three different minority contexts in Europe.
Fülöp Zsófia +3 more
doaj +1 more source
Vision: Journal for Language and Foreign Language LearningThis study investigates how Nigerian students living in an Indonesian university dormitory form beliefs about the languages in their multilingual repertoires, practice these languages across educational and social domains, and manage them in response to ...
Faris Sholakhuddin
doaj +1 more source
Enhancing learners’ reading habits through reading bags at secondary schools
Reading & Writing, 2018 The importance of getting children off to a good start in reading cannot be overstated. Successful academic performance at primary and secondary school level is partly dependent on the ability to read.
Mahlapahlapana Themane +1 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Ubiquity ProceedingsLanguage planning in higher education has traditionally been approached as a policy-driven, human-centred activity oriented towards access, equity, and multilingual inclusion.
Tobie van Dyk
doaj +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source