Results 51 to 60 of about 86,036 (308)

The idea of predestination in the Russian language picture of the world (based on dictionaries and texts of the XVIII–XIX centuries)

open access: yesГуманитарные и юридические исследования, 2022
The purpose of the article is to identify the specifics of the mythological idea of fate and its expression in the concept and in the meanings of words that verbalize it (based on the material of explanatory and encyclopedic dictionaries and in the works
V. M. Gryaznova
doaj   +1 more source

Speech Image of German Politicians as an Expression of Language Picture of the World.

open access: yes, 2013
The purpose of the article is to give a general notion of the meanings “language picture of the world” and “speech image” and identify the relationship of these meanings in cultural linguistics.
A. P. Kryachkova
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Wittgenstein's world-picture

open access: yes, 2020
In this paper, I discuss the position and meaning of Wittgenstein’s notion of “world-picture” in comparison with the central doctrines of Tractatus—the “picture-theory of meaning”—and Philosophical Investigations—“language-game” and “form of life.” This ...
Pirmohammadi Pour, Hossein
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

"THE WORLD OF ANIMALS" IN THE DIALECT LANGUAGE PICTURE OF THE WORLD

open access: yesMemoirs of NovSU
The work is devoted to the description of the dialectal linguistic picture of the world, which, being part of the general linguistic picture, differs from the latter in its natural character, reflects the peculiarities of the worldview, lifestyle and life of the people. Dialect lexicography is of great importance for
V. G. Didkovskaya, Y. I. Andreeva
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ANTROPOMORPHIC ASPECT OF SKY OBJECTS AS A DESCRIPTION OF THE MOON CONCEPT

open access: yesВестник Кемеровского государственного университета, 2015
This article deals with the description of the antropomorphic (mental, emotive, social) including vital, perceptual and bodily metaphors. Signs underlying the creation of such metaphors are explained from the mythology and symbolism perspective.
N. P. Balashova
doaj  

Helmet, Shield, and Sword as Symbolic Signs of the Warrior Concept

open access: yesВестник Кемеровского государственного университета, 2019
Attitude to Motherland plays an important role in Russian linguistic culture. The sphere is formed by a number of concepts, such as Fatherland, home, family, children, warrior, etc.
Alexei B. Bodrikov
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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