Results 51 to 60 of about 258,339 (262)

LANGUAGE PROGNOSIS AND LANGUAGE DIVERSITY IN THE RUSSIAN FEDERATION: SOCIOLINGUISTIC ASPECT

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2019
The article considers the methodological basis of sociolinguistic research into language perspectives with a focus on linguistic diversity in the Russian Federation, the study of which is closely connected with such sociolinguistic concepts as language
Aysa N. Bitkeeva   +2 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Who Cares What We Speak: A Case Study at Kgoši Mampuru Correctional Facility

open access: yesEuropean Review Of Applied Sociology, 2018
The aim of this article is to explore the dynamic of language choice and language use as well as to examine the effect of language policy on language attitudes in the Department of Correctional Services (DCS) with special reference to Pretoria Central ...
Mabule Dorah Riah
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Language Policy and Regional Varieties of the Korean Language

open access: yesPoliteja
The aim of this paper is to provide information on the language policy, planning, and management in the Republic of Korea. The research is focused on Standard Korean and the current state of Korean regional dialects.
Vladislava Mazana
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Le secteur de la santé en Algérie entre arabisation, défrancisation et anglicisation

open access: yesL’Année du Maghreb
The language issue in Algeria continues to engage Algerian society, attracts the attention of many scholars, and astonish observers with its complexity and instability.
Fatima Zohra Chebab, Karim Ouaras
doaj   +1 more source

Foreign language education in rural schools: Struggles and initiatives among generalist teachers teaching English in Mexico

open access: yesStudies in Second Language Learning and Teaching, 2021
In many countries, English as a foreign/second language (L2) teaching has become compulsory in urban and rural public schools. In rural areas, the challenges for the implementation of this state-sanctioned policy have been explored among L2 teaching ...
Jesús Izquierdo   +2 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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