Results 61 to 70 of about 1,977,604 (298)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

ACME vs PDDL: support for dynamic reconfiguration of software architectures [PDF]

open access: yes, 2012
On the one hand, ACME is a language designed in the late 90s as an interchange format for software architectures. The need for recon guration at runtime has led to extend the language with speci c support in Plastik.
Batista, Thais   +2 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Language Planning and Language Policy of the Central African Republic in the Monograph of a Central African Researcher

open access: yesУченые записки Института Африки Российской академии наук
Review of the book: Koyt M.M. (2024). Vers un changement linguistique planifié au Centrafrique. Application au modèle glottopolitique. Bangui: Editions Oubangui.
DAVYDOV Artem Vitalievich
doaj   +1 more source

Challenges encountered in the home-neighbourhood-community and school domains: An analysis of Tonga revitalisation through Fishman’s (1991) Reversing Language Shift framework

open access: yesStellenbosch Papers in Linguistics Plus, 2019
Minority language groups in Zimbabwe face many challenges as they strive for space for, and recognition of, their languages. This study focuses particularly on the Tonga language spoken in the Binga district of Zimbabwe.
Chikasha, Jubilee , Beukes, Anne-Marie
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Ebonics: The Debate Which Never Happened [PDF]

open access: yes, 1999
The thesis of this paper is that no substantive and impartial debate about the pedagogical value of using Ebonics in the classroom could be held in the United States media because America\u27s prescriptive attitude towards Ebonics does not allow fair and
Birch, Barbara
core   +2 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Fundamental Reform Document of Education and ELT Program: The Investigation of Language Teachers’ Perspectives [PDF]

open access: yesApplied Research on English Language, 2019
: The purpose of the current attitudinal study is to investigate the attitudes and opinions of language teachers toward the implemented ELT program resulted from the Fundamental Reform Document of Education in the Iranian Ministry of Education.
Mohammad Javad Ansari   +2 more
doaj   +1 more source

Building on a terminology resource – the Irish experience [PDF]

open access: yes, 2010
www.focal.ie is the national database of Irish language terminology. In this paper, we examine: (i) the impact achieved by this resource in the five year period since work commenced; (ii) the possibilities which have arisen from one project over a short ...
Bhreathnach, Úna   +2 more
core  

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