Results 61 to 70 of about 7,387,449 (340)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Dynamics of Language Shift among Lawa-Speaking Families in Northern Thailand
Journal of the Southeast Asian Linguistics Society, 2022 This paper examines Lawa language shift, vitality, and endangerment on the family level in Northern Thailand using a six-question set adapted from the five key questions of the Expanded Graded Intergenerational Disruption Scale (EGIDS).
Panyawuthakrai, Rakkhun +1 more
doaj
ATTITUDES OF INDIGENOUS ACEHNESE PEOPLE TOWARDS THEIR VERNACULAR MAINTENANCE IN LANGSA.
JL3T (Journal of Linguistics, Literature and Language Teaching), 2017 This research is a study on native people’s attitudes towards Acehnese language in Langsa Aceh. The research design used a qualitative research method that examines the attitudes of native speakers of the language of Aceh in Langsa in prewserving the ...
Fakhrurrazi Fakhrurrazi
doaj +1 more source
Language Idling and Language in Use Wittgenstein on Following Rules [PDF]
, 2002 This paper has a simple goal: it aims to present the difference between static logic and dynamic grammar. At the same time I will stress another difference which traverses logic and grammar: the difference between language idling and language in use ...
Moser, Anna Aloisia
core
Islamic Learning in Arabic-Afrikaans Between Malay Model and Ottoman Reform [PDF]
, 2015 Through the second half of the nineteenth and the first half of the twentieth century the Muslim community of Cape Town produced a large number of texts in various fields of Islamic learning, written in Afrikaans, a creolized variety of the language the ...
Versteegh, K. (Kees)
core +3 more sources
Religion, Language Maintenance, and Language Shift
, 2023 Abstract This chapter explores the role of religious practice in the linguistic changes of Roman-period Gaul, both as a conservative factor in the retention of the local language, Gaulish, and as a Latinizing factor. Epigraphic sources show that domain-based choices linked to religious practices can be a crucial factor for evaluating ...
Olivier De Cazanove +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Pergeseran Bahasa Baku: Ragam Bahasa Elitis dalam Akun Instagram Humor Recehku
Diglosia, 2021 The purpose of this study is to describe elitist language on the Humor Recehku Instagram account, namely (1) non-standard word forms; (2) abbreviated forms that cause non-standard; and (3) word forms from foreign languages.
Wiwik Ariesta +2 more
doaj +1 more source
FROM MARTO TO MARFELINO, A SHIFT IN NAMING IN GOTPUTUK VILLAGE [PDF]
, 2012 This is a study of names in a village called Gotputuk. Naming is one of language manifestation. Therefore, studying the way naming is maintained or shifted can reflect the language maintenance and shift.
Nurhayat, Nurhayat
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source