Results 81 to 90 of about 5,007,900 (357)

Recent research on child language brokering in the United Kingdom [PDF]

open access: yes, 2010
Recent patterns of migration and population change in the UK have led in some places to a need for child language brokering (CLB). Although there is only limited evidence on CLB in the UK, the research that has been published indicates the diversity of ...
Cline, Tony   +3 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Individual variability and the H* ~ L + H* contrast in English

open access: yesLanguage and Cognition
The H* ~ L + H* pitch accent contrast in English has been a matter of lengthy debate, with some arguing that L + H* is an emphatic version of H* and others that the accents are phonetically and pragmatically distinct.
Riccardo Orrico   +3 more
doaj   +1 more source

Revisiting the Neighborhood: How L2 Proficiency and Neighborhood Manipulation Affect Bilingual Processing

open access: yesFrontiers in Psychology, 2018
We conducted three neighborhood experiments with Dutch–English bilinguals to test effects of L2 proficiency and neighborhood characteristics within and between languages.
Kimberley Mulder   +3 more
doaj   +1 more source

Legalese versus plain language [PDF]

open access: yes, 2001
Article looking at developments in legal drafting, considering traditional approaches, reluctance to change, pitfalls of change and the benefits of plain language.
Butt, Peter
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Impact of Formal and Informal Pronouns of Address on Product Price Estimation

open access: yesLanguages
Previous literature has examined the effect of using a formal or informal second-person pronoun on consumers’ appreciation of an advertisement and the advertised product and their purchase intention. This is the first study that additionally examines the
Helen de Hoop   +5 more
doaj   +1 more source

Review: Conversational interaction in second language acquisition: A collection of empirical studies. [PDF]

open access: yes, 2008
This new book edited by Alison Mackey provides a clear overview of the state of research into the role of interaction in SLA, and includes 16 new studies especially written for this book.
Barnard, Roger
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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