Results 91 to 100 of about 1,037,636 (310)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The Study of Cognitive and Affective Language Attitudes of Kurdish-Persian Bilinguals Towards Standard Persian Based on Mentalist Approach [PDF]
مطالعات زبانها و گویشهای غرب ایران, 2014 In recent decades, language attitude has been one of the most important concepts in linguistic studies and more particularely in sociolinguistics. Considering the importance of language attitudes of bilinguals, this study aims at investigating language ...
Mandana Pirouzfar, Mahmoud Eliasi
doaj
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Mental Translation as a Cognitive Process in Communicative Language Teaching and Learning [PDF]
Scientific Bulletin of the Politehnica University of Timişoara: Transactions on Modern LanguagesIn EFL learning and teaching processes, mental translation might play an essential role in the mind of the foreign language learner. Some scholarly papers investigate the types of processing in the language learners’ mind such as language perception ...
Adriana TOMA
doaj
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Revista CEFACPurpose: to carry out an integrative review of literature regarding the use of the ICF in Speech-Language-Hearing Therapy. Methods: a search was conducted on both national and international databases, for articles published between 2008 and 2018 ...
Alice Prado de Azevedo Antunes +3 more
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source