Results 71 to 80 of about 2,163,570 (278)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real-Time Statistical Speech Translation

open access: yes, 2014
This research investigates the Statistical Machine Translation approaches to translate speech in real time automatically. Such systems can be used in a pipeline with speech recognition and synthesis software in order to produce a real-time voice ...
A. Radziszewski, D. Cer, F. Holz
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Testes orais individuais e em pares: um estudo das diferenças de desempenho Individual and pair speaking test formats: a study of differences in performance

open access: yesDELTA: Documentação de Estudos em Lingüística Teórica e Aplicada, 2008
O objetivo desta pesquisa foi verificar se há diferença no desempenho caso os candidatos façam o teste oral sozinhos ou em pares. Duas versões do First Certificate in English foram aplicadas para dez alunos em duas situações diferentes ...
Thaís Barbosa Marochi
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Evaluating an Online Assessment Course: Teachers’ Voices on Their Language Assessment Literacy

open access: yesProfile: Issues in Teachers' Professional Development
This article reports a mixed-methods case study on English language teachers’ evaluation of an online assessment course and their language assessment literacy.
Frank Giraldo, Xun Yan
doaj   +1 more source

A Post-Positivist and Interpretive Approach to Researching Teachers’ Language Assessment Literacy

open access: yesProfile: Issues in Teachers' Professional Development, 2020
The language assessment literacy of English language teachers has been one of the topics of discussion in the language testing field. In this article, I focus on the need to expand research constructs and methodologies to understand, in depth, the ...
Frank Giraldo
doaj   +1 more source

DEUCE : a test-bed for evaluating ESL competence criteria [PDF]

open access: yes, 2003
This paper describes work in progress to apply a Web-based facility for evaluating differing criteria for English language competence. The proposed system, Discriminated Evaluation of User's Competence with English (DEUCE), addresses the problem of ...
Ozasa, T., Weir, G.R.S.
core  

Home - About - Disclaimer - Privacy