Results 71 to 80 of about 20,812,150 (281)

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Effect of Context on the L2 Thinking for Speaking Development of Path Gestures

open access: yesL2 Journal, 2018
Different languages inherently present different thinking for speaking patterns, targeting different meaning components for expression. Previous research has demonstrated that second language learners largely tend transfer their first language thinking ...
Tasha N. Lewis
doaj  

The association between home language, self-identified Hispanic origin, and current e-cigarette use among Hispanic youth in the United States – National Youth Tobacco Survey, 2022–2023

open access: yesPreventive Medicine Reports
Objective: Cigarette smoking differs within the Hispanic population, with adults from Puerto Rico and Cuba (PRC) reporting higher percentages than those from Mexico and Central or South America. Limited research examines if there are similar patterns for
Shichen Zheng   +4 more
doaj   +1 more source

The use of Arabic in Kuwaiti EFL classrooms: An exploratory study on the patterns and functions of language choice

open access: yesCogent Education, 2017
This study examines the relationship between the functions and patterns of language choice in EFL classrooms in a Kuwaiti primary school. It applies the overall order model, specifically the medium of classroom interaction, to identify three patterns of ...
Maha Alghasab
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The patterns and prevalence of monosyllabic three-letter-word spelling errors made by South African English First Additional Language learners

open access: yesSouth African Journal of Childhood Education, 2017
There is growing evidence of systematic underachievement of South African primary school learners in reading in English as the first additional language.
Brahm Fleisch   +2 more
doaj   +1 more source

BioPatML- an XML description language for patterns in biological sequences [PDF]

open access: yes, 2007
Background: A major challenge in computational biology is the description of biological systems in a way that allows their computational evaluation and exchange between institutes and applications.
Towsey, Michael W.   +5 more
core  

The development of the passé composé in lower-intermediate learners of French as a second language [PDF]

open access: yes, 2008
In this study we tracked the development of the passe compose in second-language learners of French whose first language is English. Although the passe compose is a highly used tense among native speakers of French and it appears to present particular ...
Graham, Suzanne Jane, Macaro, Ernesto
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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