Results 71 to 80 of about 384,957 (303)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Literacy Trek, 2019 This study was set out to investigate a small number of Turkish EFL teachers’ views about the concepts of a standard language, dialects, and other language varieties concerning their mother tongue (Turkish) and the language (English) they are tasked with
Ferhat Üresin, Ali Karakaş
doaj
Absolute spatial deixis and proto-toponyms in Kata Kolok [PDF]
, 2014 This paper presents an overview of spatial deictic structures in Kata Kolok, a sign language which is indigenous to a Balinese village community. Sociolinguistic surveys and lexicographic comparisons have indicated that Kata Kolok is unrelated to the ...
De Vos, Connie
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Eesti ja Soome-ugri Keeleteaduse Ajakiri, 2011 A central issue of this paper is to study the patterns invariation of attitudes toward minority language varieties in four minority communities from Hungary: German, Slovak, Serb and Romanian.
Anna Borbely
doaj +1 more source
Conflicting Tendencies in the Development of Scientific and Technical Language Varieties: Metaphorization vs. Standardization [PDF]
, 2014 The present paper discusses relations between meaning and context as an interactive process that promotes cognition and communication, both intralingual and interlingual.
Iļjinska, Larisa, Smirnova, Tatjana
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Linguistik OnlineThe paper aims to propose a reflection on the importance of German varieties in the preparation of interpreters. Like many other languages, German is classified as a pluricentric language, i. e.
Miriam Morf
doaj +1 more source
Euskaldunek euskalkienganako izan dituzten jarrerez
Anuario del Seminario de Filología Vasca "Julio de Urquijo", 1992 The aim of this essay is to gather together all accounts of the attitudes of the speakers of Basque (euskaldunes) towards the various varieties of the Basque language.
Koldo Zuazo
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source