Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
TEACHING FOREIGN LANGUAGES FOR SPECIFIC PURPOSES: MOTIVATION AND COOPERATIVE LEARNING
One of the most notable features of recent years in the field of linguistics and didactics of foreign languages is the increase of interest in languages for specific purposes.
Enkela DALIPI
doaj
THE IMPACT OF CROSS-CULTURAL COMMUNICATION ON BUSINESS TERMINOLOGY LEARNING [PDF]
In today’s globalized business environment, cross-cultural communication plays a crucial role in facilitating collaboration and understanding among professionals from diverse linguistic and cultural backgrounds.
Anamaria Mirabela Pop, Monica Ariana Sim
doaj
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Automatic sentence simplification system for Arabic Script Punjabi. [PDF]
Shehzad T +4 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Validation of the Adaptive Danish Sentence Test (DAST): Normative Data from a Template-Based, Linguistically Rich Sentence-in-Noise Test. [PDF]
Kressner AA +4 more
europepmc +1 more source
LANGUAGE FOR SPECIFIC PURPOSES IN NEUROSCIENCE
openaire +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
The include network: Advancing cross-linguistic equity in brain health research. [PDF]
García AM +13 more
europepmc +1 more source

