Química Nova, 2012 A UV-spectrophotometric method is described for the determination of lansoprazole (LAN). The method is based on the measurement of the absorbance of LAN solution in acetonitrile at 281 nm. The system obeyed Beer's law over the concentration range of 1.25-
Zenita Devi Okram +3 more
doaj +1 more source
Repositioning proton pump inhibitors as anticancer drugs by targeting the thioesterase domain of human fatty acid synthase [PDF]
, 2014 Fatty acid synthase (FASN), the enzyme responsible for de novo synthesis of free fatty acids, is up-regulated in many cancers. FASN is essential for cancer cell survival and contributes to drug resistance and poor prognosis.
Fako, Valerie E. +4 more
core +5 more sources
Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.This study evaluated pharmacogenomic (PGx) calling from whole‐exome sequencing (WES) in 3562 Taiwanese individuals. Fourteen pharmacogenes were reliably identified, with each person carrying an average of ~2.4 actionable phenotypes. The high actionable frequencies of G6PD deficiency and HLA‐B*58:01 highlight ethnic differences and support WES as a ...
Hsu‐Heng Lin +9 more
wiley +1 more source
Possibilities for prescribing lansoprazole in the outpatient practice
Медицинский совет, 2019 Acid-dependent diseases are an urgent problem of modern gastroenterology. Antisecretory agents are first-line drugs in the treatment of this pathology, the leaders among which are proton pump inhibitors (PPI). Due to the wide representation of this group
I. G. Pakhomova, E. Yu. Pavlova
doaj +1 more source
\u3cem\u3eHelicobacter pylori\u3c/em\u3e infection in Havana, Cuba. Prevalence and \u3cem\u3ecagA\u3c/em\u3e status of the strains [PDF]
, 2005 There is a great paucity of information about Helicobacter pylori infection in the countries of the Caribbean basin. Almost no studies have been performed to determine the prevalence, antibiotic resistance or virulence factors of the bacterium.
Camou-Juncas, Christine +12 more
core +1 more source
Lansoprazole inhibits the cysteine protease legumain by binding to the active site
Basic & Clinical Pharmacology & Toxicology, 2019 Proton pump inhibitors (PPIs) are prodrugs used in the treatment of peptic ulcer diseases. Once activated by acidic pH, the PPIs subsequently inhibit the secretion of gastric acid by covalently forming disulphide bonds with the SH groups of the parietal ...
T. Bosnjak +5 more
semanticscholar +1 more source
The effect of lansoprazole administration during pregnancy on the placenta
Journal of Basic Research in Medical Sciences, 2017 Introduction: Lansoprazole is one of the proton pump inhibitor drugs widely used in the treatment of gastro-duodenal ulcers and disorders. However, there is not enough data about unexplored adverse effects of lansoprazole on the integrity of the ...
Ali Louei Monfared, Morteza Shamsi
doaj
Rational Selection Of Proton Pump Inhibitors (Ppis) Through An Objective Scoring System For Effective Formulary Management [PDF]
, 2011 Pemilihan ubat secara rasional adalah penting dalam pengurusan formulari yang berkesan.
Lim, Lynette, Chu Ann
core +1 more source
Quantitative sensory testing in painful hand osteoarthritis demonstrates features of peripheral sensitisation. [PDF]
, 2012 Hand osteoarthritis (HOA) is a prevalent condition for which treatments are based on analgesia and physical therapies. Our primary objective was to evaluate pain perception in participants with HOA by assessing the characteristics of nodal involvement ...
Ejindu, V +5 more
core +2 more sources
In Vitro Evaluation of Eslicarbazepine Delivery via Enteral Feeding Tubes [PDF]
, 2017 Purpose: The feasibility of preparing an eslicarbazepine acetate suspension using Aptiom tablets for administration via enteral feeding tubes was evaluated.
Dave, Vivek S +3 more
core +2 more sources