The Pharmacogenetics of Cytochrome P450 2C19 Enzymes - Effects on Clopidogrel and Proton Pump Inhibitors [PDF]
BACKGROUND: Cytochrome P450 (CYP) enzymes play important roles in human, including drug metabolism. CYP2 is the largest family of human CYP, with its sequence comprising almost one third of all CYP sequences, and responsible for the metabolism of ...
Muliaty, D. (Dewi) +1 more
core +4 more sources
Proton Pump Inhibitors Therapy in Children with Gastroesophageal Reflux [PDF]
Proton pump inhibitors (PPI) has been widely used by clinicians to treat diseases that require suppression of gastric acid. PPI work by inhibiting the proton pump in gastric parietal cells.In adult patients, PPI hasbeen widely studied and showed ...
Hegar, B. (Badriul), Reynaldo, A. (Aldo)
core
PDB140 Quality of Care For Patients With Diabetes Mellitus (Dm) In Canada: Findings From A National Population-Based Survey [PDF]
Núm. de Catàleg de Patrimoni: 2076Primer pla d'una operària netejant una troballa d'estris de metall, a les excavacions realitzades sota el pis de la Sala Capitular del Monestir de Santa Maria de Pedralbes des de finals de 2007 i fins a principis de ...
Szabo, SM +3 more
core +1 more source
Impact of creatinine clearance on helicobacter pylori eradication rate in patients with peptic ulcer disease [PDF]
Introduction. Gastrointestinal complaints are common in patients with kidney failure. The aim of this study was to investigate the effect of creatinine clearance on Helicobacter pylori (HP) eradication rate in patients with peptic ulcer disease ...
Alimadadi, M. +6 more
core
Rational Selection Of Proton Pump Inhibitors (Ppis) Through An Objective Scoring System For Effective Formulary Management [PDF]
Pemilihan ubat secara rasional adalah penting dalam pengurusan formulari yang berkesan.
Lim, Lynette, Chu Ann
core +1 more source
[Excerpt] The FDA’s regulation of drugs is frequently the subject of policy debate, with arguments falling into two camps. On the one hand, a libertarian view of patients and the health care system holds high the value of consumer choice.
Cohen, I. Glenn, Price, W. Nicholson, II
core +1 more source
What medications are safe and effective for heartburn during pregnancy? [PDF]
Ranitidine is the best-studied agent effective for treatment of heartburn in pregnancy. Some antacids are effective, but it may be prudent to avoid them in the first trimester until better safety studies are published. Although sucralfate, metoclopromide,
Koenig, Clint (Clint J.), 1971-
core
Background/Aims: The CYP2C19 polymorphism plays an important role in the metabolism of various proton-pump inhibitors. Several trials have produced conflicting data on eradication rates of Helicobacter pylori (H. pylori) among CYP2C19 genotypes.
doaj +1 more source
An Exploratory Analysis of Pharmaceutical Price Disparities and Their Implications Among Six Developed Nations [PDF]
In our study of 43 drugs, prescription drug prices in several wealthy nations (Australia, Canada, France, Germany, and the U.K.) were much lower than in the U.S. on average, well below relative per capita GDP. There was relatively little difference among
Elizabeth DuPre +2 more
core
What regimens eradicate Heliobacter pylori? [PDF]
Fourteen-day triple therapy with a proton pump inhibitor (PPI) plus clarithromycin and either amoxicillin or metronidazole is superior to 7-day therapy in eradicating Heliobacter pylori (strength of recommendation [SOR]: A, highquality meta-analysis ...
Malaty, Wail, Stigleman, Sue
core

