Results 31 to 40 of about 10,268 (212)

Lymphocytic Colitis Associated with Lansoprazole Treatment

Current Therapeutic Research, 2007
There have been several reported cases of lansoprazole-associated collagenous colitis (CC) reported in the literature but only 1 reported case of lansoprazole-associated lymphocytic colitis (LC) in the literature. Both CC and LC are considered inflammatory bowel diseases, but they are distinctly classified based on the condition of the colon, which is ...
Alagozlu, Hakan, Dursun, Ayse, Tuncer, Candan, Simsek, Zahide   +3 more
openaire   +4 more sources

Predicting OCT2/MATEs‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

Clinical Pharmacology &Therapeutics, EarlyView.
Organic cation transporter (OCT) 2 and multidrug and toxin extrusion (MATE) transporters play significant roles in the renal secretion of organic cations and drug–drug interactions (DDIs). Recent in vitro studies indicate that the Ki values for OCT2 exhibit substrate dependency and increase in potency with pre‐incubation.
Satoshi Asano, Aleksandra Galetin, Yoshiko Tomita, Kathleen M. Giacomini, Xiaoyan Chu, Xinning Yang, Toshimichi Nakamura, Hiroyuki Kusuhara, Yuichi Sugiyama   +8 more
wiley   +1 more source

Insights Into Patient‐Level Exposure to Actionable Pharmacogenomic Medications in Australia Using a New National Pharmacogenomic Guideline

Clinical Pharmacology &Therapeutics, EarlyView.
This study assessed the use of 35 pharmacogenomic (PGx) medications listed in the Royal College of Pathologists of Australasia (RCPA) guideline, estimated the potential costs of subsidizing PGx testing in Australia, and predicted related prescribing changes.
Bella D. Ianni, Chin Hang Yiu, Mohammad A. Ali, Christine Y. Lu   +3 more
wiley   +1 more source

Elevated tissue transglutaminase immunoglobulin A: Celiac disease or polytypic plasmacytosis?

JPGN Reports, EarlyView.
Abstract We report a case of an adolescent girl post cardiac transplant with hypergammaglobulinemia and presumed celiac disease (CD), who had a persistently elevated anti‐tissue transglutaminase immunoglobulin A despite a gluten free diet. Refractory CD and Crohn's disease were excluded.
Andrew Turunen, Aisha Ahmed, Philip Thrush, Paula North, Ankur Chugh   +4 more
wiley   +1 more source

Anorectal gastric heterotopia as a rare cause of constipation: Case report and review of pediatric literature

JPGN Reports, EarlyView.
Abstract Gastric heterotropia (GHT) may present from the oropharynx to the anus and is commonly associated with Meckel's diverticula. Here, we describe a rare case of anorectal GHT localized to the distal anal canal. A 14‐month‐old male patient presented for evaluation of rectal bleeding, severe constipation, and abdominal distention with poor response
Kathryn M. Stephenson, Raj P. Kapur, Jeffrey R. Avansino, Lusine Ambartsumyan   +3 more
wiley   +1 more source

Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Background Oxaliplatin‐induced peripheral neuropathy (OIPN) is a major clinical challenge because it leads to discontinuation of chemotherapy. Omeprazole, a proton pump inhibitor (PPI), has been shown to prevent OIPN in a rat model. Therefore, we aimed to test whether the concomitant use of a PPI reduces oxaliplatin discontinuation due to OIPN.
Keisuke Mine, Takehiro Kawashiri, Kohei Mori, Yusuke Mori, Haruna Ishida, Hibiki Kudamatsu, Shunsuke Fujita, Mayako Uchida, Takaaki Yamada, Nobuaki Egashira, Ichiro Ieiri, Satoru Koyanagi, Shigehiro Ohdo, Takao Shimazoe, Daisuke Kobayashi   +14 more
wiley   +1 more source

Risk Factors for Microscopic Colitis: A Systematic Review and Meta‐Analysis

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Microscopic colitis (MC) is still an underdiagnosed disease due to its primarily histological appearance. We aimed to address the scarcity and inconsistency of data on MC risk factors. Methods Our protocol was prospectively registered in PROSPERO (CRD42022286624).
Anett Rancz, Brigitta Teutsch, Mahmoud Obeidat, Anna Walter, Gergő Weidinger, Bálint Erőss, Péter Hegyi, Emese Mihály   +7 more
wiley   +1 more source

Olmesartan‐induced gastritis with no lower gastrointestinal symptoms: A case report

DEN Open, Volume 6, Issue 1, April 2026.
Abstract A 74‐year‐old man with decreased appetite, weight, and heartburn was referred to our hospital. His medications included olmesartan. Esophagogastroduodenoscopy (EGD) revealed antral‐dominant erosive gastritis and nodular mucosa. A gastric biopsy revealed inflammatory cell infiltration.
Satoshi Kosaka, Miki Kamiyama, Masahiro Ochi   +2 more
wiley   +1 more source

Hydroxylation of lansoprazole in poor metabolizers of CYP2C19 [PDF]

British Journal of Clinical Pharmacology, 2005
We read the recent paper by Saito et al.[1] with interest. The theme of their paper was quite similar to the one we published 6 years ago [2]. However, there was one curious point in the results. Individuals with the poor metabolizer (PM) genotype of CYP2C19 lack the CYP2C19 enzyme therefore hydroxylation of lansoprazole is assumed to be mediated by ...
Akira Hishida, Mitsushige Sugimoto, Naohito Shirai, Takahisa Furuta, Akiko Nakamura   +4 more
openaire   +3 more sources

Efektivitas Pemberian Antibiotik Disertai Lansoprazol pada Refluks Laringofaring dengan Infeksi Helicobacter pylori

Majalah Kedokteran Bandung, 2012
Laryngopharyngeal Reflux (LPR) is a reflux of gastric content to the laryngopharyngeal and influenced by Helicobacter pylori infection. The treatment of H. pylori infection consists of proton pump inhibitor and two kinds of antibiotics, i.e.
Yanti Nurrokhmawati, Teti Madiadipoera, Ratna Anggraeni, Tonny Basriyadi Sarbini   +3 more
doaj   +1 more source