Results 51 to 60 of about 18,195 (260)

Impact of Long-Term Proton Pump Inhibitor Therapy on Gut Microbiota in F344 Rats: Pilot Study

open access: yesGut and Liver, 2016
Background/Aims To evaluate changes in gut microbiota composition following long-term proton pump inhibitor (PPI) treatment. Methods : Twenty-four-week-old F344 rats were fed diets with (n=6) or without (n=5) lansoprazole for 50 weeks.
Cheol Min Shin   +11 more
doaj   +1 more source

Insights Into Patient‐Level Exposure to Actionable Pharmacogenomic Medications in Australia Using a New National Pharmacogenomic Guideline

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This study assessed the use of 35 pharmacogenomic (PGx) medications listed in the Royal College of Pathologists of Australasia (RCPA) guideline, estimated the potential costs of subsidizing PGx testing in Australia, and predicted related prescribing changes.
Bella D. Ianni   +3 more
wiley   +1 more source

Proton-pump inhibitor use is associated with a broad spectrum of neurological adverse events including impaired hearing, vision, and memory. [PDF]

open access: yes, 2019
Proton-pump inhibitors, PPIs, are considered effective therapy for stomach acid suppression due to their irreversible inhibition of the hydrogen/potassium pump in the gastric parietal cells. They are widely prescribed and are considered safe for over-the-
Abagyan, Ruben   +4 more
core   +1 more source

Pretreatment of Garlic Oil Extracts Hampers Epithelial Damage in Cell Culture Model of Peptic Ulcer Disease

open access: yesMedicina, 2022
Background and Objectives: Peptic ulcer disease is a chronic disease affecting up to 10% of the world’s population. Proton pump inhibitors, such as lansoprazole are the gold standard in the treatment of ulcer disease.
Lucija Kuna   +9 more
doaj   +1 more source

Hydroxylation of lansoprazole in poor metabolizers of CYP2C19 [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2005
We read the recent paper by Saito et al.[1] with interest. The theme of their paper was quite similar to the one we published 6 years ago [2]. However, there was one curious point in the results. Individuals with the poor metabolizer (PM) genotype of CYP2C19 lack the CYP2C19 enzyme therefore hydroxylation of lansoprazole is assumed to be mediated by ...
Akira Hishida   +4 more
openaire   +3 more sources

Anorectal gastric heterotopia as a rare cause of constipation: Case report and review of pediatric literature

open access: yesJPGN Reports, EarlyView.
Abstract Gastric heterotropia (GHT) may present from the oropharynx to the anus and is commonly associated with Meckel's diverticula. Here, we describe a rare case of anorectal GHT localized to the distal anal canal. A 14‐month‐old male patient presented for evaluation of rectal bleeding, severe constipation, and abdominal distention with poor response
Kathryn M. Stephenson   +3 more
wiley   +1 more source

Perbandingan Efektivitas antara Omeprazol dan Lansoprazol terhadap Perbaikan Kualitas Hidup Penderita Rinosinusitis Kronik Akibat Refluks Laringofaring

open access: yesMajalah Kedokteran Bandung, 2012
Laryngopharyngeal reflux (LPR) is the reflux of gastric acid through the esophagus that reaches laringopharyngeal area. The prevalence of LPR in the range 15–20%, and caused chronic rhinosinusitis (CRS).
Tantri Kurniawati   +3 more
doaj   +1 more source

Rethinking psychological treatment targets for pediatric rumination syndrome: Clinical implications from a case series analysis

open access: yesJPGN Reports, EarlyView.
Abstract Rumination syndrome (RS) is a common pediatric disorder of gut–brain interaction. However, a dearth of research on efficacious treatment to help guide clinical decision‐making remains. Thus, relying on well‐established treatment recommendations for other conditions with similar mechanisms or symptom profiles may be helpful; for example ...
William A. Piña‐Anastasiadis   +8 more
wiley   +1 more source

Erosive Eosinophilic Esophagitis in Rumination Syndrome [PDF]

open access: yes, 2009
Rumination syndrome involves bringing up partially digested food into the pharynx voluntarily, followed by reswallowing or expelling. It was discovered in the 17th century; however, knowledge of the disorder has remained sparse until recently.
Rick, James R, Sidhu, Shawn S
core   +2 more sources

A New Synthetic Process of Lansoprazole.

open access: yesChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Hyun Tae Shin   +6 more
openaire   +4 more sources

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