Results 31 to 40 of about 16,188 (197)

Treatment of Digital Ulcers and Reflux Oesophagitis in a Patient with Systemic Sclerosis: Increased Risk of Hepatotoxicity due to a Potential Drug-drug Interaction Between Bosentan and Vonoprazan

open access: yesActa Dermato-Venereologica, 2021
is missing (Short communication)
Ryoko Kimura   +4 more
doaj   +1 more source

Comparison of lansoprazole-based triple and dual therapy for treatment of Helicobacter pylori-related duodenal ulcer: An Asian multicentre double-blind randomized placebo controlled study [PDF]

open access: yes, 2000
Background: In Asian countries with limited resources, clarithromycin-based triple therapy may not be readily available. There are also few direct comparisons of different regimens in Asia. Aim: To compare two lansoprazole-based non-clarithromycin triple
Carpio, RE   +17 more
core   +1 more source

Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurity in Lansoprazole

open access: yesE-Journal of Chemistry, 2010
An unknown impurity in lansoprazole (2-[[[3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridyl] methyl] sulfinyl] benzimidazole) was detected by HPLC and was identified as des-(trifluoroethoxy) lansoprazole, an principal synthetic route indicative impurity of ...
K. S. V Srinivas   +3 more
doaj   +1 more source

The proton-pump inhibitor lansoprazole enhances amyloid beta production.

open access: yesPLoS ONE, 2013
A key event in the pathogenesis of Alzheimer's disease (AD) is the accumulation of amyloid-β (Aβ) species in the brain, derived from the sequential cleavage of the amyloid precursor protein (APP) by β- and γ-secretases.
Nahuai Badiola   +8 more
doaj   +1 more source

Electrochemical behavior of lansoprazole at a multiwalled carbon nanotubes-ionic liquid modified glassy carbon electrode and its electrochemical determination [PDF]

open access: yesJournal of the Serbian Chemical Society, 2014
The electrochemical behavior of lansoprazole (LNS) has been investigated at a glassy carbon electrode (GCE) and the electrode modified by a gel containing multiwalled carbon nanotubes (MWCNTs) and an room-temperature ionic liquid (RTIL) of 1 ...
Liu Li-Hong   +3 more
doaj   +1 more source

Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers [PDF]

open access: yes, 2019
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Upregulation of the CAIX/XII isoforms is associated with hypoxic tumours and clinically linked with malignant progression, treatment ...
Gieling, Roben, Williams, Kaye J.
core   +2 more sources

Comparative analysis of the effect of PO administered acid suppressants on gastric pH in healthy cats

open access: yesJournal of Veterinary Internal Medicine, 2020
Background Proton pump inhibitors (PPIs) are among the most commonly prescribed medications for esophagitis and upper gastrointestinal erosion and ulceration in cats.
Phillip Ryan   +7 more
doaj   +1 more source

Effectiveness of ranitidine bismuth citrate and proton pump inhibitor based triple therapies of Helicobacter pylori in Turkey [PDF]

open access: yesLibyan Journal of Medicine, 2011
Background : Helicobacter pylori infection is the main cause of gastritis, gastroduodenal ulcer disease, MALT lymphoma, and adenocarcinoma of the stomach. The reported prevalence of H. pylori in the adult population in Turkey is 67.6%–81.3%.
Mustafa Iscan, Feriha Oz, Huseyin Alkim
doaj   +1 more source

Comparison of hepatotoxicity of tegoprazan, a novel potassium-competitive acid blocker, with proton pump inhibitors using real-world data: A nationwide cohort study

open access: yesFrontiers in Medicine, 2023
BackgroundProton pump inhibitors (PPIs) are acid suppressants that are frequently prescribed in many countries to reduce heartburn. A potassium-competitive acid blocker (P-CAB; tegoprazan) was launched relatively recently that also inhibits gastric acid ...
Min-Gul Kim   +16 more
doaj   +1 more source

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