Results 41 to 50 of about 160,761 (259)

Rare Case of Ileal Perforation [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Ileitis, or inflammation of the ileum, is often caused by Crohn’s disease. However, ileitis may be caused by a wide variety of other diseases.
Vinod Kumar B   +4 more
doaj   +1 more source

Thirty-day mortality in patients undergoing laparotomy for small bowel obstruction.

open access: yes, 2018
BACKGROUND: Small bowel obstruction (SBO) is a common indication for emergency laparotomy. There are currently variations in the timing of surgery for patients with SBO and limited evidence on whether delayed surgery affects outcomes.
Anderson, I   +7 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

ORGAN-PRESERVING INTERVENTIONS IN SURGICAL CORRECTION OF SPLEEN CYSTS IN CHILDREN

open access: yesActa Medica Leopoliensia, 2023
The surgical approach to splenic cyst treatment in children is rather controversial. There are different organ-preserving surgeries available to treat children with the spleen affected by cystic lesions.
Andriy Kuzyk
doaj   +1 more source

Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy

open access: yes, 2019
Background: The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in
Borda-Luque, Giuliano   +14 more
core   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

open access: yesAdvanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li   +15 more
wiley   +1 more source

Comparison between opioid-based anaesthesia technique and opioid-free anaesthesia technique in patients undergoing laparotomy for gynaecological malignancy: A randomised controlled trial

open access: yesIndian Journal of Anaesthesia
Background and Aims: To investigate whether opioid-free anaesthesia (OFA) or opioid-based anaesthesia (OBA) technique with ultrasound (US)-guided rectus sheath block (RSB) provides early recovery and less opioid-related side effects in patients ...
Reshma Kalagara   +5 more
doaj   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

Procedures in obstetrics and gynaecology [PDF]

open access: yes, 2010
Book providing practical approach to broad range of procedures in obstetrics and gynaecology.
Jeffery, Stephen
core   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

open access: yesAdvanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen   +10 more
wiley   +1 more source

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