Results 51 to 60 of about 160,761 (259)

Laparotomy

, 1980
Laparotomy of the left side is the approach of choice for surgery of the rumen, reticulum and some reproductive and urinary tract conditions, explorations of the viscera and inguinal hernia repair in the ...
Hamilton, G. F.
core   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Isolated gallbladder perforation after blunt abdominal trauma in children

African Journal of Paediatric Surgery, 2013
Injury of the gallbladder after blunt abdominal trauma is rare. Isolated contusion of the gallbladder is exceptional because of its anatomical localization. It is protected by the liver, intestines, the omentum, and ribs.
Oumar Ndour, Helle Moustapha, Ndeye Aby Ndoye, Gabriel NGom   +3 more
doaj   +1 more source

Intraoperative lung protective ventilation in peritonitis patients undergoing emergency laparotomy: A randomised controlled trial

Indian Journal of Anaesthesia, 2021
Background and Aims: Lung protective ventilation (LPV) is recommended in acute respiratory distress syndrome. However, role of intraoperative LPV in elective laparotomy is controversial and it has not been evaluated in emergency laparotomy (EL).
Apala Roy Chowdhury, Rajkumar Subramanian, Souvik Maitra, Sulagna Bhattacharjee, Ramakrishnan Lakshmy, Dalim Kumar Baidya   +5 more
doaj   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Perioperative emergency laparotomy pathway for patients undergoing emergency laparotomy: A propensity score matched study

Introduction: Emergency laparotomy (EL) is associated with high morbidity and mortality, often exceeding 10%. This study evaluated the impact of the EMergency Laparotomy Audit (EMLA) interdisciplinary perioperative pathway on patient outcomes, hospital ...
Vincent Zhiwei Yeow, Faheem Khan, Emergency Laparotomy Group, Jonathan Ming Jie Yeo, Christine Xia Wu, Janardhan Baliga, Joel Wen Liang Lau, Philip Iau, Stephanie Teo, Tracy Jia Hui Goh, Ying Xin Teo   +10 more
core   +1 more source

Pelvic Inflammatory Disease Presenting as Acute Peritonitis in an Australian Rural Center

Journal of Surgical Specialties and Rural Practice
A 38-year-old female presented to a rural emergency department with peritonitis, severe right upper quadrant pain, and abdominal distension. Blood tests revealed elevated inflammatory markers, and imaging was inconclusive for acute cholecystitis.
Joshua Sungho Hong, Kaushik Joshi, Prasenjit Modak, Shantha Tellambura   +3 more
doaj   +1 more source

Laparoscopy Versus Laparotomy in Ectopic Pregnancy [PDF]

, 2015
Background: Ectopic pregnancy (EP) is the implantation of fertilized ovum in any site of the reproductive tract except uterine cavity. To choose laparotomy or laparoscopy for treatment is based on the patient’s hemodynamic status, her past surgical ...
Ahmadi, Farahnaz, Ghajarzadeh, Mahsa, Davari Tanha, Fatemeh   +2 more
core   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source