Results 41 to 50 of about 2,523 (255)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Material removal mode of lapping Si₃N₄balls

Jin'gangshi yu moliao moju gongcheng, 2019
To explore the effect of grinding parameters on surface quality and the mechanism of material removal mode in lapping process, lapping experiment on Si3N4 bearing balls was carried out by vertical grinder.
ZHANG Ke, WANG Dingwen, LI Songhua, SUN Jian, WU Yuhou   +4 more
doaj  

A Study on Correcting Techniques for Recovering the Accracy of a Deteriorated Lapping Plate using a Correcting Carrier (Corrective Characteristics owing to Lapping Pressure Influence).

JSME international journal. Ser. 3, Vibration, control engineering, engineering for industry, 1992
At present, the accuracy of a deteriorated lapping plate may be recovered by cutting and grinding, or by using a correcting carrier. A correcting carrier is simpler to use than the grinding method and is generally employed at many factories. How-ever, as the deteriorated condition of the lapping plate changes with machining conditions, optimal ...
ICHIKAWA, Kohichiro, ISHIKAWA, Ken-ichi, SUWABE, Hitoshi, TAKAGI, Hiroyuki   +3 more
openaire   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Machining characteristics of single crystal SiC wafer with copper lapping pad

Jin'gangshi yu moliao moju gongcheng, 2016
The Siface and C face of 6H-SiC single crystal wafer were lapped by using the copper based lapping pad with spiral grooves and the effects of lapping pressure,pad speed and abrasive size on the material removal rate and the surface roughness of SiC were ...
LIANG Huazhuo, LU Jiabin, YAN Qiusheng
doaj  

Effects of Lapping Parameters and Slurry Type on Machining Performance of Sapphire Fairings with Controllable Texture Diamond Tools

Journal of Applied Science and Engineering
Three diamond film tools with controllable texture were fabricated prepared by chemicalvapor deposition (CVD) method. Their surface quality was analysed, and the tools were innovatively used to lap sapphire fairing.
Feng Wei, Zhou Shuai, Sun Xiaokang, Lu Wenzhuang   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Mechanistic Features of Nanodiamonds in the Lapping of Magnetic Heads

The Scientific World Journal, 2014
Nanodiamonds, which are the main components of slurry in the precision lapping process of magnetic heads, play an important role in surface quality.
Xionghua Jiang, Zhenxing Chen, Joy Wolfram, Zhizhou Yang   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source