Results 71 to 80 of about 144,814 (257)

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Time to Endovascular Treatment and Clinical Outcome in Acute Ischemic Stroke With M2‐Segment Occlusion

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In large vessel occlusion (LVO) stroke, shorter time from stroke onset to endovascular thrombectomy (EVT), and faster recanalization in the early window (
Sterre Dassen, Adriaan van Es, Bob Roozenbeek, Rob van de Graaf, Yvo Roos, Charles Majoie, Elyas Ghariq, Nyika Kruyt, Urs Fischer, Robert van Oostenbrugge, Wim van Zwam, Julie Staals   +11 more
doaj   +1 more source

Asymmetrical Bioimpedance in the Anterior Circulation for Urgent Stratification of suspected Stroke (ABACUS Stroke): study protocol for a diagnostic accuracy study

Diagnostic and Prognostic Research, 2020
Background Early identification and treatment of stroke improve outcome. Ischaemic stroke due to large vessel occlusion (LVO) benefits from time-critical thrombectomy but this is only available in highly specialised healthcare services.
Christopher I. Price, Lisa Shaw, Anand Dixit, Sara Graziadio, Clare Lendrem, Dipayan Mitra, Helen Rodgers, Lou Sutcliffe, Phil White   +8 more
doaj   +1 more source

Association between time to reperfusion and outcome is primarily driven by the time from imaging to reperfusion [PDF]

, 2016
Background and Purpose A progressive decline in the odds of favorable outcome as time to reperfusion increases is well known. However, the impact of specific workflow intervals is not clear.; Methods We studied the mechanical thrombectomy group (n=103 ...
Cerda, Neus, Cobo Valeri, Erik, Dávalos Errando, Antoni, Jovin, Tudor G., Molina, Carlos A., Ribó, Marc, Sanroman, Luis, Tomasello, Alejandro, Urra, Xabier   +8 more
core   +2 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Timing of vessel imaging for suspected large vessel occlusions does not affect groin puncture time in transfer patients with stroke. [PDF]

, 2018
BACKGROUND: Access to endovascular therapy (ET) in cases of acute ischemic stroke may be limited, and rapid transfer of eligible patients to hospitals with endovascular capability is needed.
Dhamoon, Mandip S., Fifi, Johanna T., Liang, John W., Stein, Laura, Tuhrim, Stanley, Wilson, Natalie   +5 more
core   +1 more source

The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund. It is shared under the Creative Commons License Attribution-Noncommercial No Derivative 3.0 (CCBY NCND).
Carter, SE, Faulkner, A, Rakobowchuk, M
core   +1 more source

Elastomeric Micro‐Balloons for Remote Control of Cerebral Blood Flow and Real‐Time In vivo Imaging of Rodent Brain Response to Hypoperfusion

Advanced Materials, EarlyView.
This study reports the fabrication of MRI‐compatible elastomeric micro‐balloons via a multi‐step bubble casting process, where the monolithic elastomeric wall is selectively stiffened for reversible and controlled inflation and elasticity, depending on the target vessels for graded occlusion of cerebral arteries.
Jong Bin Kim, Jinghui Wang, Yinding Chi, Jingxian Wu, Alicia Ng, Guanda Qiao, Honglin Tan, Miroslaw Janowski, Piotr Walczak, Yajie Liang, Shu Yang   +10 more
wiley   +1 more source

Editor's choice : European Society for Vascular Surgery (ESVS) 2020 clinical practice guidelines on the management of acute limb ischaemia

, 2020
A
Acosta, Stefan, Azuma, Nobuyoshi, Bastos Gonçalves, Frederico, Björck, Martin, Boyle, Jonathan R., Chakfé, Nabil, Choke, Edward T. C., Cochennec, Frederic, Cohnert, Tina U., de Borst, Gert J., Document Reviewers, Earnshaw, Jonothan J., ESVS Guidelines Committee, Fitridge, Robert A., Forbes, Thomas L., Hamady, Mohamad S., Hinchliffe, Robert, Jongkind, Vincent, Kakkos, Stavros K., Koelemay, Mark J. W., Koncar, Igor, Lindholt, Jes S., Mani, Kevin, Menyhei, Gabor, Munoz, Alberto, Müller-Hülsbeck, Stefan, Rai, Kumud, Sebastian Debus, E., Svetlikov, Alexei V., Tshomba, Yamume, Tulamo, Riikka, van den Berg, Jos C., Vega de Ceniga, Melina, Vermassen, Frank   +33 more
core   +2 more sources

Prehospital neurological deterioration in stroke [PDF]

, 2018
BACKGROUND AND PURPOSE: Patients with stroke can experience neurological deterioration in the prehospital setting. We evaluated patients with stroke to determine factors associated with prehospital neurological deterioration (PND).
Adeoye, Opeolu, Alwell, Kathleen, De Los Rios La Rosa, Felipe, Ferioli, Simona, Flaherty, Matthew L., Kissela, Brett M., Kleindorfer, Dawn O., Mackey, Jason, Martini, Sharyl, McMullan, Jason, Moomaw, Charles J., Slavin, Sabreena J., Sucharew, Heidi, Woo, Daniel   +13 more
core   +1 more source