Results 71 to 80 of about 87,000,110 (295)

Association between pre-pregnancy body weight and dietary pattern with large-for-gestational-age infants in gestational diabetes

Diabetology & Metabolic Syndrome, 2019
Background Both obesity and gestational diabetes (GDM) are associated with adverse outcomes. Diet during pregnancy impacts weight gain and fetal growth. Therefore, we aimed to explore non-pharmacological treatment success depending on pre-pregnancy body ...
Ana Munda, Marjanca Starčič Erjavec, Katja Molan, Jerneja Ambrožič Avguštin, Darja Žgur-Bertok, Draženka Pongrac Barlovič   +5 more
doaj   +1 more source

Insulin Resistance in Hispanic Large-for-Gestational-Age Neonates at Birth [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2007
Intrauterine exposure to maternal diabetes and large size at birth are known risk factors for the subsequent development of insulin resistance and metabolic syndrome. Although Hispanic youth have been shown to have a high prevalence of metabolic syndrome, it is unknown whether metabolic abnormalities and a predisposition for glucose intolerance are ...
Jennifer Shine, Dyer, Charles R, Rosenfeld, Julie, Rice, Mark, Rice, Dana S, Hardin   +4 more
openaire   +2 more sources

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

The gestational age‐specific difference in birthweight between singletons born after fresh and frozen embryo transfer: A cohort study

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction Accumulating studies have suggested singletons born after frozen embryo transfer (FET) were higher than those born after fresh embryo transfer (Fre‐ET).
Qiaoqiao Ding, Yuhuan Wang, Lu Suo, Yue Niu, Dingying Zhao, Yunhai Yu, Daimin Wei   +6 more
doaj   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Change of maternal weight gain trajectory following lifestyle interventions for gestational diabetes and its impact on abnormal infant birthweight: an observational study based on longitudinal weight measurements

BMC Pregnancy and Childbirth
Background Restricted gestational weight gain (GWG) following lifestyle interventions for gestational diabetes mellitus (GDM) has been observed in clinical trials but not been explicitly confirmed in real-world clinical settings.
Juan Li, Chuanzi Yang, Kuanrong Li
doaj   +1 more source

Association between maternal lipid profiles and vitamin D status in second trimester and risk of LGA or SGA: a retrospective study

Frontiers in Endocrinology
BackgroundAccumulating evidence has linked dyslipidemia during pregnancy to the risk of delivering infants born either large for gestational age (LGA) or small for gestational age (SGA). However, the effects of the vitamin D status on these relationships
Xianhua Zheng, Kefeng Lai, Chengyi Liu, Yuan Chen, Xiaodan Zhang, Weixiang Wu, Mingyong Luo, Chunming Gu   +7 more
doaj   +1 more source

Differential classification of infants in United States neonatal intensive care units for weight, length, and head circumference by United States and international growth curves

Annals of Human Biology, 2020
Background Clinicians and researchers use a variety of intrauterine growth curves to classify NICU infants as small (SGA), appropriate (AGA), or large for gestational age (LGA).
A. Nicole Ferguson, Irene E. Olsen, Reese H. Clark, Bryan D. Yockey, Jonathan Boardman, Kyle Biron, Cooper Jannuzzo, Daniel Waskiewicz, Amanda Mendoza, M. Louise Lawson   +9 more
doaj   +1 more source

Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight

, 2019
ObjectiveNonalcoholic fatty liver disease (NAFLD) is a well-recognized hepatic manifestation of metabolic disease in adults and has been associated with the development of gestational diabetes (GDM).
Won Kim, Ja Nam Koo (7309814), Chan-Wook Park, Sun Min Kim, Seung Mi Lee, Sue Shin, Sae Kyung Joo (4401715), Gyoung Min Kim, Sae Kyung Joo, Sang Youn Kim (6053744), Jong Kwan Jun, Jong Kwan Jun (7309832), Joong Shin Park (7309835), Chanthalakeo Vixa, Ig Hwan Oh, Soo Heon Kwak (7309826), Chanthalakeo Vixa (7309829), Byoung Jae Kim, Sue Shin (652479), Gyoung Min Kim (7309823), Ig Hwan Oh (7309820), Seung Mi Lee (317488), Byoung Jae Kim (7309811), Won Kim (437999), Errol R Norwitz, Soo Heon Kwak, Errol R. Norwitz (7309817), Ja Nam Koo, Joong Shin Park, Sun Min Kim (421876), Sang Youn Kim, Chan-Wook Park (317492)   +31 more
core   +1 more source