Results 101 to 110 of about 10,828,663 (311)

Octagonal large-mode-area leakage channel fiber with reduced bending loss

open access: yes, 2010
We investigate a novel design for high-power large-mode-area leakage channel fibers (LCFs) with a single octagonal dual-diameter air-hole ring encircling a nine-cell pure-silica core, having a tenfold differential mode loss and increased resistance to ...
Lorenzo Rosa (4053517)   +10 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Large on-chip Brillouin net amplification in silicon-based nano-photonics

open access: yesAIP Advances, 2019
Recent developments in on-chip forward Brillouin scattering open up potential applications such as RF photonic signal processing, on-chip Brillouin amplification, and on-chip Brillouin lasers.
Hyeongpin Kim, Heedeuk Shin
doaj   +1 more source

Laporan Mei 2019 Perpustakaan Universitas Medan Area

open access: yes, 2019
66 HalamanPuji syukur kepada Allah SWT, karena atas Karunia dan Rahmat-Nya laporan bulanan Perpustakaan Universitas Medan Area Bulan Mei 2019 dapat tersusun dengan baik.
Perpustakaan, Universitas Medan Area
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A Micro Saddle Coil with Switchable Sensitivity for Local High-Resolution Imaging of Luminal Tissue

open access: yesMicromachines, 2016
This paper reports on a micro saddle coil for local high-resolution magnetic resonance imaging (MRI) fabricated by embedding a flexible coil pattern into a polydimethyilsiloxane (PDMS) tube.
Tetsuji Dohi, Kousuke Murashige
doaj   +1 more source

Single-Mode Solid-Core Tellurite Glass Fiber with Large Mode Area and Low Loss for Infrared Applications

open access: yes, 2009
We report the fabrication of a single-mode solid-core tellurite glass fiber with large mode area of 103 μm2 and low loss of 0.24~0.7 dB/m at 1550 nm. By using continuous-wave self-phase modulation method, the non-resonant nonlinear refractive index n2
林傲祥 (Aoxiang Lin)   +4 more
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Laporan Januari 2019 Perpustakaan Universitas Medan Area

open access: yes, 2019
68 HalamanPuji syukur kepada Allah SWT, karena atas Karunia dan Rahmat-Nya laporan bulanan Perpustakaan Universitas Medan Area Bulan Januari 2019 dapat tersusun dengan baik.
Perpustakaan, Universitas Medan Area
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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