Results 81 to 90 of about 10,828,663 (311)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
High-Power Emission via Large-Area VCSELs With Single High-Order Mode Operation
IEEE Photonics JournalIn this work we investigate patterned large-active area AlGaAs vertical-cavity surface-emitting lasers (VCSELs) targeting high-power single-transverse-mode emission.
Valerio Torrelli +5 more
doaj +1 more source
Williamsburg Area Bicyclists Records
, 2006 Primarily issues of the newsletter of the Williamsburg Area Bicyclists, "The Flying Wheel," dated from July 2006 to May 2007. There is also artwork, recurring advertisements, and information on the production of the newsletter.
Williamsburg Area Bicyclists
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Advances in Silica-Based Large Mode Area and Polarization-Maintaining Photonic Crystal Fiber Research. [PDF]
Materials (Basel), 2022 Ma Y, Wan R, Li S, Yang L, Wang P.
europepmc +1 more source
Cutoff properties of large-mode-area photonic crystal fibers
, 2005 The cutoff properties of triangular photonic crystal fibers with different core dimensions have been deeply investigated. In particular, 7-rod core fibers, obtained by removing the air-holes belonging to the first ring, as well as the central one in the ...
Lorenzo Rosa (4053517) +4 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Limitation on effective area of bent large-mode-area leakage channel fibers
, 2011 We investigate the bending characteristics of leakage channel fibers (LCFs) to achieve large mode area (LMA) and effectively single-mode operation with a practically allowable bending radius for compact Yb-doped fiber applications.
Lorenzo Rosa (4053517) +8 more
core +1 more source
Large-area single-mode photonic bandgap vcsels [PDF]
, 2003 We demonstrate that the photonic bandgap effect can be used to control the modes of large area vertical cavity surface emitting lasers.
S. Bischoff +11 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source