Results 41 to 50 of about 330,462 (300)

Design and Analysis of a Large Mode Field Area and Low Bending Loss Multi-Cladding Fiber with Comb-Index Core and Gradient-Refractive Index Ring

Sensors, 2023
The large mode field area fiber can raise the tolerance of power, and high requirements for the bending characteristics of optical fibers are needed. In this paper, a fiber composed of a comb-index core, gradient-refractive index ring, and multi-cladding
Yining Zhang, Yudong Lian
doaj   +1 more source

Large mode area fiber lasers and their applications [PDF]

Advanced Solid State Lasers, 2000
The area of fiber lasers has undergone rapid developments in recent years. Gone are the days when fiber lasers were seen as something of an irrelevant curiosity, offering interesting performance features, but always with power levels or other performance limitations, that made them unsuitable for all but a few applications.
Richardson, D.J., Offerhaus, H.L., Broderick, N.G.R.   +2 more
openaire   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Large-mode-area fibers operating near single-mode regime

Optics Express, 2016
Lower NA in large-mode-area fibers enables better single-mode operation and larger core diameters. Fiber NA has traditionally been limited to 0.06, mostly due to the control tolerance in the fabrication process. It has been recognized recently that transverse mode instability is a major limit to average power scaling in fiber lasers.
Fanting, Kong, Christopher, Dunn, Joshua, Parsons, Monica T, Kalichevsky-Dong, Thomas W, Hawkins, Maxwell, Jones, Liang, Dong   +6 more
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

High-Order Modes Suppression in All-Glass Large-Mode Area Rare-Earth Doped Optical Fibers with Modified Cladding

Photonics, 2022
In the present work we have developed and realized a high core-to-cladding diameters ratio active optical fibers operated in a single-mode regime due to specially designed structure containing boron-doped and fluorine-doped rods.
Svetlana S. Aleshkina, Maxim M. Khudyakov, Tatiana A. Kashaykina, Mikhail V. Yashkov, Mikhail Yu. Salganskii, Vladimir V. Velmiskin, Mikhail M. Bubnov, Mikhail E. Likhachev   +7 more
doaj   +1 more source

Delamination resistant composites by interleaving bio-based long-chain polyamide nanofibers through optimal control of fiber diameter and fiber morphology [PDF]

, 2020
In this work an innovative electrospinning system is proposed that simultaneously has an adequate temperature resistance, a high increase in mode I (þ51%) and mode II (þ96%) delamination performance and can be commercially produced.
Daelemans, Lode, De Clerck, Karen, Meireman, Timo, Rahier, Hubert, Rijckaert, Sander, Van Paepegem, Wim   +5 more
core   +2 more sources

Anisotropic tapered polarization-maintaining large mode area optical fibers

Optics Express, 2017
We demonstrate a novel type of tapered large mode area polarization-maintaining fiber. These birefringent fibers have an elliptical inner cladding and a core diameter that increases adiabatically from 8 µm to 70 µm. The polarization maintaining ability of the fiber samples was investigated by measuring the spatial distribution of polarization beat ...
Ustimchik, V. E., Rissanen, J., Popov, S. M., Chamorovskii, Y. K., Nikitov, S. A.   +4 more
openaire   +4 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Bending performance of large mode area multi-trench fibers

Optics Express, 2013
Bending performance of the Multi-trench Fibers (MTFs) has been investigated using the Finite Element Method. Numerical investigations show that MTFs can provide low-loss effective single mode operation under bent configuration, thanks to the resonant coupling of the Higher order Modes (HOMs).
Jain, Deepak, Baskiotis, Catherine, Sahu, Jayanta Kumar   +2 more
openaire   +4 more sources