Results 51 to 60 of about 13,162,473 (330)

Electronic cleansing in computed tomography colonography using AT layer identification with integration of gradient directional second derivative and material fraction model

open access: yesBMC Medical Imaging, 2017
Background In computed tomography colonography images, electronic cleansing (EC) is applied to remove opacified residual materials, called fecal-tagging materials (FTM), using positive-contrast tagging agents and laxative to facilitate polyp detection ...
Krisorn Chunhapongpipat   +4 more
doaj   +1 more source

On the accurate large-scale simulation of ferrofluids [PDF]

open access: yesACM Transactions on Graphics, 2019
We present an approach to the accurate and efficient large-scale simulation of the complex dynamics of ferrofluids based on physical principles. Ferrofluids are liquids containing magnetic particles that react to an external magnetic field without solidifying.
Libo Huang   +2 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

A Lasserre SDP Rounding Approximation Algorithm for Max Directed 3-Section

open access: yesTsinghua Science and Technology
We consider the Max Directed 3-Section problem, which is closely connected to other well-known graph partition problems, such as Max Cut and Max Bisection.
Guangfeng Li   +3 more
doaj   +1 more source

Large Scale Distributed Simulation on the Grid [PDF]

open access: yesSixth IEEE International Symposium on Cluster Computing and the Grid (CCGRID'06), 2006
The developmentof many complex siumulation applications requires collaborrrtive effortfrom reseachers with different domain knowledge and expertise,possibly at different locations. These simulations systems often require huge computing resources and data set, which may be geo- graphically distribyted, In ordr to support collaborative model development ...
Georgios Theodoropoulos 0001   +7 more
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Large-scale simulations of clusters of galaxies [PDF]

open access: yesAIP Conference Proceedings, 2001
We discuss some of the computational challenges encountered in simulating the evolution of clusters of galaxies. Eulerian adaptive mesh refinement (AMR) techniques can successfully address these challenges but are currently being used by only a few groups.
Ricker, P. M.   +11 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A NOT operation on Majorana qubits with mobilizable solitons in an extended Su–Schrieffer–Heeger model

open access: yesNew Journal of Physics, 2015
Coupling Majorana qubits with other qubits is absolutely essential for storing, manipulating and transferring information for topological quantum computing.
Ye Xiong, Peiqing Tong
doaj   +1 more source

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