Results 71 to 80 of about 3,450,202 (313)

Synergistic sonothrombolysis based on coaxial confocal dual-frequency focused ultrasound and vortex beams

Ultrasonics Sonochemistry
Focused ultrasound (FU) acts as a non-invasive targeted therapy for thrombus dissolution, leveraging its mechanical and cavitation effects. The thrombolysis efficiency can be markedly improved with the incorporation of an assisted focused acoustic vortex
Tinghui Meng, Zelin Sheng, Tingzhen Feng, Gepu Guo, Qingyu Ma   +4 more
doaj   +1 more source

Large scale multiagent simulation on the grid [PDF]

CCGrid 2005. IEEE International Symposium on Cluster Computing and the Grid, 2005., 2005
Simulating large scale, distributed systems of autonomous decision-makers, e.g. global logistics supply networks, is a huge challenge for hardware and software infrastructure as well as managing the process of simulation. Facing this challenge, we are going to introduce an architecture for large scale grid-based simulation infrastructure to enable high
Ingo J. Timm, Dirk Pawlaszczyk
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Impacts of spatial resolution and representation of flow connectivity on large-scale simulation of floods

, 2017
. Global-scale river models (GRMs) are core tools for providing consistent estimates of global flood hazard, especially in data-scarce regions. Due to former limitations in computational power and input datasets, most GRMs have been developed to use ...
C. Mateo, Dai Yamazaki, Hyungjun Kim, Adisorn Champathong, J. Vaze, Taikan, Oki   +6 more
semanticscholar   +1 more source

New Trends in Large Scale Distributed Systems Simulation

Journal of Algorithms & Computational Technology, 2011
In this paper we present recent developments in the domain of modeling and simulation of large scale distributed systems (LSDS). Such systems possess features that include resource sharing, openness, concurrency, scalability, fault-tolerance, and ...
Ciprian Dobre, Florin Pop, Valentin Cristea   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A novel sliding mode control with MRAS inertia identification for permanent magnet synchronous motors

Measurement + Control
To enhance the anti-inertia disturbance ability of permanent magnet synchronous motor (PMSM) speed system, an adaptive sliding mode control with inertia identification is proposed.
Zhe Song, Xi Xiao, Jun Yang, Tao Tao, Xuesong Mei   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Large-Scale Molecular Dynamics Simulation of the Dehydration of a Suspension of Smectite Clay Nanoparticles

Journal of Physical Chemistry C, 2020
Fine-grained sediments and sedimentary rocks play important roles in a variety of modern energy technologies from petroleum geology to geological carbon sequestration and radioactive waste manageme...
T. Underwood, I. Bourg
semanticscholar   +1 more source