Results 121 to 130 of about 3,127,622 (352)
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
The Astrophysical JournalGalaxies are biased tracers of the underlying cosmic web, which is dominated by dark matter (DM) components that cannot be directly observed. Galaxy formation simulations can be used to study the relationship between DM density fields and galaxy ...
Victoria Ono +5 more
doaj +1 more source
On the Mass Dependence of the Inner Slopes of Dark Matter Density Profiles
Open Astronomy, 2014 We study through a semi-analytic model how the inner slopes of relaxed ΛCDM dark matter halos with and without baryons depend on the halo mass. We find that the inner logarithmic density slope, α ≡ d log ρ/d log r, of dark matter halos with baryons has a
Del Popolo A.
doaj +1 more source
Combinatorial Properties of Finite Models [PDF]
arXiv, 2010 We study countable embedding-universal and homomorphism-universal structures and unify results related to both of these notions. We show that many universal and ultrahomogeneous structures allow a concise description (called here a finite presentation).
arxiv
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Simulation of large-scale structure of Universe with Gaussian random fields
Вісник Астрономічної школи, 2017 Large-scale structure includes galaxy clusters connected by filaments. Voids occupy the rest of cosmic volume. In this work we simulated two-dimensional galaxy distribution using random distributions of clusters and single galaxies.
A. V. Tugay, V. V. Voytsehovsky
doaj +1 more source
arXiv, 1999 The model of the universe is considered in which background of the universe is not defined by the matter but is a priori specified as a homogenous and isotropic flat space. The scale factor of the universe follows the linear law. The scale of mass changes proportional to the scale factor. This leads to that the universe has the fractal structure with a
arxiv
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Structure of the Universe: An Approach Based on Gravitational Energy [PDF]
arXiv, 2002 An approach to modelling the universe based on the requisites of gravitational energy. This model is explained as it relates to the stages of the universal life cycle and the continued existence of the universe as it is known today. The article attempts to reconcile the most common problems with physical models of the universe and overcome doubt as to ...
arxiv
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source