Results 51 to 60 of about 430,537 (306)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Cross Correlation between the Thermal Sunyaev–Zeldovich Effect and the Integrated Sachs–Wolfe Effect

open access: yesThe Astrophysical Journal Supplement Series
We present a joint cosmological analysis of the power spectra measurement of the Planck Compton parameter and the integrated Sachs–Wolfe (ISW) maps. We detect the statistical correlation between the Planck thermal Sunyaev–Zeldovich (tSZ) map and ISW data
Ayodeji Ibitoye   +7 more
doaj   +1 more source

X-ray sources as tracers of the large-scale structure in the Universe

open access: yes, 2000
We review the current status of studies of large-scale structure in the X-ray Universe. After motivating the use X-rays for cosmological purposes, we discuss the various approaches used on different angular scales including X-ray background multipoles ...
Barcons, X.   +3 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Is the Lambda CDM Model Consistent with Observations of Large-Scale Structure?

open access: yes, 2000
The claim that large-scale structure data independently prefers the Lambda Cold Dark Matter model is a myth. However, an updated compilation of large-scale structure observations cannot rule out Lambda CDM at 95% confidence. We explore the possibility of
AE Evrard   +12 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Accurate N-body simulations with local primordial non-Gaussianities: Initial conditions and aliasing

open access: yesAstronomy & Astrophysics
The new generation of galaxy surveys designed to constrain local primordial non-Gaussianity (PNG) requires N-body simulations that accurately reproduce its effects.
Adame Adrian Gutierrez   +5 more
doaj   +1 more source

The Aemulus Project. V. Cosmological Constraint from Small-scale Clustering of BOSS Galaxies

open access: yesThe Astrophysical Journal, 2023
We analyze clustering measurements of BOSS galaxies using a simulation-based emulator of two-point statistics. We focus on the monopole and quadrupole of the redshift-space correlation function, and the projected correlation function, at scales of 0.1 ...
Zhongxu Zhai   +8 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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