Results 71 to 80 of about 166,709,059 (292)
Environmental history of filament galaxies
Astronomy & AstrophysicsGalaxy properties, such as stellar mass and star formation rate, correlate with their position within the cosmic web. Although galaxy properties can be correlated with a specific environment at a certain cosmic epoch, they may have experienced different ...
Zakharova D. +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Astronomy & AstrophysicsThe high value of the cosmic microwave dipole may be telling us that dark matter is macroscopic rather than a fundamental particle. The possible presence of a significant dark matter component in the form of primordial black holes (PBHs) suggests that ...
Mould Jeremy
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The reason peculiar velocities grow faster in general relativity than in Newtonian gravity
Astronomy & AstrophysicsContext. We provide a theoretical comparison between the Newtonian and quasi-Newtonian studies and the general relativistic analysis of linear cosmological peculiar velocities, in view of the increasing number of surveys reporting bulk peculiar flows ...
Pasten Erick, Tsagas Christos G.
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Inflationary Imprints on the Large Scale Structure of the Universe
, 2022 Inflation is the predominant model describing the early universe, however we do not know much about the underlying theory, besides, there are other open questions in cosmology, for example about the nature of dark matter and dark energy.
Tranquilli, Nicola
core
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
The density and velocity fields of the local universe. [PDF]
, 1999 We present two self-consistent non-parametric models of the local cosmic velocity field based on the density distribution in the PSCz redshift survey of IRAS galaxies.
Teodoro, Luís Filipe Alves
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source