Results 1 to 10 of about 62,694 (156)

Pulmonary Large Cell Neuroendocrine Carcinoma

Pathology and Oncology Research, 2022
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rare subtype of malignant pulmonary tumor. The incidence rate of LCNEC was reported to be 0.3%–3% in lung cancers.
Lan Yang, Lan Yang, Lan Yang, Lan Yang, Ying Fan, Ying Fan, Ying Fan, Ying Fan, Hongyang Lu, Hongyang Lu, Hongyang Lu, Hongyang Lu   +11 more
doaj   +3 more sources

Pulmonary large cell carcinoma with neuroendocrine morphology shows genetic similarity to large cell neuroendocrine carcinoma [PDF]

Diagnostic Pathology, 2022
Background Large cell neuroendocrine carcinoma (LCNEC) is a high-grade malignant pulmonary neuroendocrine tumour. The distinction of pulmonary large cell carcinoma (LCC) and LCNEC is based on the presence of neuroendocrine morphology and the expression ...
Zuoyu Liang, Weiya Wang, Qianrong Hu, Ping Zhou, Ying Zhang, Yuan Tang, Qian Wu, Yiyun Fu, Xue Li, Yang Shao, Lili Jiang   +10 more
doaj   +3 more sources

Management of Large Cell Neuroendocrine Carcinoma [PDF]

Frontiers in Oncology, 2021
BackgroundLarge cell neuroendocrine carcinoma (LCNEC) is a rare, aggressive cancer with a dismal prognosis. The majority of cases occur in the lung and the gastrointestinal tract; however, it can occur throughout the body.
Virginia Corbett, Susanne Arnold, Lowell Anthony, Aman Chauhan   +3 more
doaj   +3 more sources

Rectal large cell neuroendocrine carcinoma. [PDF]

Oxf Med Case Reports
Abstract Rectal large cell neuroendocrine carcinoma (LCNEC) is an exceedingly rare and aggressive neoplasm with a poor prognosis and median survival of 4–16 months. Diagnosis is challenging due to the clinical overlap with classical colorectal adenocarcinoma, and accurate diagnosis is reliant on histological examination via ...
Drakos PA, Prountzopoulou AA, Totskas E, Stamou K.   +3 more
europepmc   +3 more sources

Clinical characterization of pulmonary large cell neuroendocrine carcinoma and large cell carcinoma with neuroendocrine morphology [PDF]

Cancer, 2001
Large cell carcinoma has been classified as four potential types based on its neuroendocrine morphology and evidence of neuroendocrine differentiation discernible by immunohistochemistry or electron microscopy. However, the clinical relation among these four categories has not been clearly defined.
Akira Iyoda, K Hiroshima, Tetsuya Toyozaki   +2 more
exaly   +3 more sources

Successful treatment of large-cell neuroendocrine carcinoma of the prostate with pembrolizumab: a case report [PDF]

Journal of Medical Case Reports
Background Large-cell neuroendocrine carcinoma of the prostate is an extremely rare disease and classified into two subtypes: de novo and treatment-induced large-cell neuroendocrine carcinoma that arises from adenocarcinoma via lineage plasticity in ...
Erika Yamashita, Shingo Ashida, Rie Yoshimura, Ryohei Iga, Yoshitaka Kurano, Shinkuro Yamamoto, Tsutomu Shimamoto, Hideo Fukuhara, Satoshi Fukata, Atsushi Kurabayashi, Takashi Karashima, Keiji Inoue   +11 more
doaj   +2 more sources

A case report of primary large cell neuroendocrine carcinoma of the urinary bladder [PDF]

Urology Case Reports
Neuroendocrine carcinoma (NEC) is a highly malignant tumor that originates from neuroendocrine cells, most commonly found in the gastrointestinal tract and lungs.
Yuan Liu, Qi Wang
doaj   +2 more sources

Hepatic metastasis of pulmonary large cell neuroendocrine carcinoma: A case report and literature review [PDF]

Journal of International Medical Research
Large cell neuroendocrine carcinoma of the lung is a rare and aggressive malignancy with a high propensity for metastasis. This carcinoma demonstrates a significantly higher propensity for hepatic metastasis compared with other non-small cell lung cancer
Jiake Wu, Yang Cai, Bei Lu, Yanan Xu, Jianyong Zhuo, Junjie Yin   +5 more
doaj   +2 more sources

Primary large-cell neuroendocrine carcinoma of the prostate [PDF]

Archives of the Balkan Medical Union, 2022
Introduction. Depending on neuroendocrine differentiation, the prostate cancer is divided into two major groups: primary neuroendocrine prostate tumour (carcinoid, small-cell, and large-cell neuroendocrine carcinoma) or as a focal tumour in conventional ...
Spasimir T. SHOPOV
doaj   +1 more source

Combined Large-Cell Neuroendocrine and Squamous Cell Carcinoma of the Uterine Cervix with a Personal History of the Primary Breast Duct Carcinoma in situ: A Clinicopathological Characteristic and Outcome

Case Reports in Oncology, 2022
Squamous cell carcinoma admixed with large-cell neuroendocrine carcinoma of the uterine cervix is an extremely rare malignancy with a poor prognosis. We report a 50-year-old woman with mixed squamous cell carcinoma and large-cell neuroendocrine carcinoma
Duc Thanh Le, Kien Hung Do, Tu Anh Do, Hoai Thu Thi Bui, Chu Van Nguyen   +4 more
doaj   +1 more source