Results 21 to 30 of about 11,794,837 (186)
A Case of Bladder Large Cell Carcinoma with Review of the Literature
Neuroendocrine (NE) tumors of the bladder are infrequent. Among them, large cell NE tumor has been outlined only in case reports and short case series, which describes them as aggressive malignancies with dismal prognosis requiring a multidisciplinary ...
Paolo Lopedote +2 more
doaj +1 more source
Metastatic neuroendocrine carcinoma to the mandibular gingiva from the duodenum papilla
Neuroendocrine carcinoma is a high-grade carcinoma with morphological and immunohistochemical features of neuroendocrine differentiation. Poorly differentiated neuroendocrine carcinoma which has two subtypes (small cell or large cell type) is extremely ...
Toshinori Iwai +3 more
doaj +1 more source
Large-cell neuroendocrine tumor of the prostate: a case report and review of the literature
Background Primitive neuroendocrine prostate neoplasms are rarely reported. This entity comprises carcinoïd tumors and poorly differentiated neuroendocrine tumors, mainly those of the small-cell type. Large-cell-type primitive tumors are exceptional, and
Walid Sleiman +9 more
doaj +1 more source
Hypopharyngeal large cell neuroendocrine carcinoma [PDF]
Neuroendocrine carcinoma (NEC) of the head and neck is rare. We report a case of a 56-year-old man with a 6-week history of dysphagia, a neck mass and weight loss. He was diagnosed with a hypopharyngeal large cell NEC (LCNEC) with metastases to multiple sites. He received two cycles of cisplatin and etoposide.
Wei-I, Lee +3 more
openaire +2 more sources
Background Neuroendocrine neoplasms are extremely rare and account for 0.4% to 2% of all malignant esophageal neoplasms. The burden of the neuroendocrine histological type on the patients’ prognosis and survival is poorly debated.
Francisco TUSTUMI +5 more
doaj +1 more source
Update on large cell neuroendocrine carcinoma [PDF]
High-grade neuroendocrine carcinomas of the lung are classified into two categories: large cell neuroendocrine carcinoma (LCNEC) and small cell lung carcinoma (SCLC). While typical cases of LCNEC are morphologically distinct from SCLC, the differentiation between LCNEC and SCLC can be challenging in some cases.
Kenzo, Hiroshima, Mari, Mino-Kenudson
openaire +2 more sources
Molecular Characterization and Prognostication of Large Cell Neuroendocrine Carcinoma and Large Cell Carcinoma [PDF]
PurposeLarge cell neuroendocrine carcinoma (LCNEC) and classic large cell carcinoma (LCC) are two distinct entities with different histological and biological characteristics. However, the mutational profiles and the clinical behavior of the two subtypes of lung cancer remain to be explored.Patients and MethodsPathological diagnoses of all screened ...
Ying Chen +7 more
openaire +3 more sources
Herein, we summarize two rare cases of salivary neuroendocrine carcinoma arising in the parotid gland. The patients were a 54-year-old Japanese female and a 74-year-old Japanese male.
Hiroshi Harada +6 more
doaj +1 more source
Expression of a neuroendocrine gene signature in gastric tumor cells from CEA 424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. [PDF]
A large fraction of murine tumors induced by transgenic expression of SV40 large T antigen (SV40 TAg) exhibits a neuroendocrine phenotype. It is unclear whether SV40 TAg induces the neuroendocrine phenotype by preferential transformation of progenitor ...
Georg Enders (187983) +32 more
core +1 more source
Large Cell Neuroendocrine Carcinoma [PDF]
Large cell neuroendocrine carcinoma (LCNEC) was originally separated from atypical carcinoids based on a worse prognosis. It is characterized by neuroendocrine morphology and expression of neuroendocrine markers. The cells are larger compared to SCLC and possess enlarged nucleoli and a coarse chromatin.
Helmut Popper, Bruno Murer
openaire +2 more sources

