Results 1 to 10 of about 789,939 (119)

Pulmonary large cell carcinoma with neuroendocrine morphology shows genetic similarity to large cell neuroendocrine carcinoma

Diagnostic Pathology, 2022
Background Large cell neuroendocrine carcinoma (LCNEC) is a high-grade malignant pulmonary neuroendocrine tumour. The distinction of pulmonary large cell carcinoma (LCC) and LCNEC is based on the presence of neuroendocrine morphology and the expression ...
Zuoyu Liang, Weiya Wang, Qianrong Hu, Ping Zhou, Ying Zhang, Yuan Tang, Qian Wu, Yiyun Fu, Xue Li, Yang Shao, Lili Jiang   +10 more
doaj   +1 more source

A Case of Bladder Large Cell Carcinoma with Review of the Literature

Case Reports in Oncology, 2022
Neuroendocrine (NE) tumors of the bladder are infrequent. Among them, large cell NE tumor has been outlined only in case reports and short case series, which describes them as aggressive malignancies with dismal prognosis requiring a multidisciplinary ...
Paolo Lopedote, Amir Yosef, Olga Kozyreva   +2 more
doaj   +1 more source

Combined large cell neuroendocrine carcinoma and squamous cell carcinoma of the oropharynx: A collision course of tumors

Clinical Case Reports, 2022
Combined large cell neuroendocrine carcinoma (LCNEC) and squamous cell carcinoma (SCC) of the H&N are exceptionally rare. We present the case of combined p16 negative SCC and LCNEC of the oropharynx treated with combination chemotherapy.
Nicholas A. Rossi, Rachelle Gietzen, Lauren T. Malaya, Kareem B. Haroun, Grant R. Conner, Orly Coblens, Vicente A. Resto, Cecilia G. Clement, Rohan Joshi   +8 more
doaj   +1 more source

Molecular Characterization and Prognostication of Large Cell Neuroendocrine Carcinoma and Large Cell Carcinoma

Frontiers in Oncology, 2022
PurposeLarge cell neuroendocrine carcinoma (LCNEC) and classic large cell carcinoma (LCC) are two distinct entities with different histological and biological characteristics. However, the mutational profiles and the clinical behavior of the two subtypes
Ying Chen, Xiaoying Cui, Di Wang, Guojie Xia, Minyan Xing, Lei Cheng, Liming Sheng, Xianghui Du   +7 more
doaj   +1 more source

Pulmonary Large Cell Neuroendocrine Carcinoma

Pathology and Oncology Research, 2022
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rare subtype of malignant pulmonary tumor. The incidence rate of LCNEC was reported to be 0.3%–3% in lung cancers.
Lan Yang, Lan Yang, Lan Yang, Lan Yang, Ying Fan, Ying Fan, Ying Fan, Ying Fan, Hongyang Lu, Hongyang Lu, Hongyang Lu, Hongyang Lu   +11 more
doaj   +1 more source

Management of Large Cell Neuroendocrine Carcinoma

Frontiers in Oncology, 2021
BackgroundLarge cell neuroendocrine carcinoma (LCNEC) is a rare, aggressive cancer with a dismal prognosis. The majority of cases occur in the lung and the gastrointestinal tract; however, it can occur throughout the body.
Virginia Corbett, Susanne Arnold, Lowell Anthony, Aman Chauhan   +3 more
doaj   +1 more source

Pulmonary Combined Large Cell Neuroendocrine Carcinoma

Pathology and Oncology Research, 2022
Pulmonary combined large-cell neuroendocrine carcinoma (CLCNEC) is a rare neuroendocrine tumor pertained to lung large cell neuroendocrine carcinoma (LCNEC) with aggressive behavior and poor prognosis generally.
Meihui Li, Meihui Li, Meihui Li, Meihui Li, Lan Yang, Lan Yang, Lan Yang, Hongyang Lu, Hongyang Lu, Hongyang Lu   +9 more
doaj   +1 more source

Mixed Small Cell and Large Cell Neuroendocrine Carcinoma of the Endometrium

Philippine Journal of Pathology, 2021
Neuroendocrine carcinoma (NEC) of the endometrium is a rare, aggressive subtype of endometrial cancer.  We report a 61-year-old female with a history of breast cancer, s/p modified radical mastectomy, chemotherapy, radiotherapy and hormonal (tamoxifen ...
Joshua Uyboco, Mary Anne Cruz, Maria Concepcion Cenizal, Jeffrey So, Maximino Bello, Jose Moran   +5 more
doaj   +1 more source

Combined Large-Cell Neuroendocrine and Squamous Cell Carcinoma of the Uterine Cervix with a Personal History of the Primary Breast Duct Carcinoma in situ: A Clinicopathological Characteristic and Outcome

Case Reports in Oncology, 2022
Squamous cell carcinoma admixed with large-cell neuroendocrine carcinoma of the uterine cervix is an extremely rare malignancy with a poor prognosis. We report a 50-year-old woman with mixed squamous cell carcinoma and large-cell neuroendocrine carcinoma
Duc Thanh Le, Kien Hung Do, Tu Anh Do, Hoai Thu Thi Bui, Chu Van Nguyen   +4 more
doaj   +1 more source

THE PROGNOSIS OF THE DIFFERENT ESOPHAGEAL NEUROENDOCRINE CARCINOMA SUBTYPES: A POPULATION-BASED STUDY

Arquivos de Gastroenterologia, 2022
Background Neuroendocrine neoplasms are extremely rare and account for 0.4% to 2% of all malignant esophageal neoplasms. The burden of the neuroendocrine histological type on the patients’ prognosis and survival is poorly debated.
Francisco TUSTUMI, Stefanie Sophie Buuck MARQUES, Esau Furini BARROS, Alexandre Cruz HENRIQUES, Jaques WAISBERG, André Roncon DIAS   +5 more
doaj   +1 more source