Results 131 to 140 of about 84,841 (279)

Rectal metastasis from lung cancer diagnosed by endoscopic ultrasound‐guided fine needle biopsy: A case report

DEN Open, Volume 6, Issue 1, April 2026.
Abstract A 73‐year‐old man visited our hospital due to hyperintestinal peristalsis and diarrhea. He had been undergoing regular annual checkups for dust lung disease. Contrast‐enhanced computed tomography scan showed edematous thickening of the rectal wall with contrast effect.
Shinji Mukawa, Yudai Koya, Tomoyuki Murakami, Koichiro Miyagawa, Yuki Maruno, Koki Yamaguchi, Shun Hanada, Shinji Oe, Masaru Harada   +8 more
wiley   +1 more source

Clinicopathologic Disease Characteristics and Their Association with Adjuvant Chemotherapy Outcomes in Pulmonary Large-Cell Carcinoma Patients with or Without Neuroendocrine Features

Diagnostics
Background: Large-cell carcinoma (LCC) and large-cell neuroendocrine carcinoma (LCNEC) are kinds of rare lung tumors classified as distinct forms of non-small-cell lung cancer (NSCLC).
Doğan Bayram, Oznur Bal, Efe Cem Erdat, Serhat Sekmek, Saliha Yılmaz, Perihan Perkin, Süleyman Gökalp Güneş, Efnan Algin, Bülent Mustafa Yenigün   +8 more
doaj   +1 more source

Endoscopic features of deficient mismatch repair/microsatellite instability‐high and BRAF‐mutated colorectal cancer

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objective Recent advancements in genome analyses, including the BRAF gene and mismatch repair (MMR) gene/microsatellite instability (MSI), have revealed the biological diversity of colorectal cancer (CRC). BRAF‐mutated CRC has a poor prognosis; however, cases exhibiting deficient MMR (dMMR)/MSI‐high (MSI‐H) and BRAF gene mutations have ...
Rika Omote, Shizuma Omote, Ryohei Sumii, Joichiro Horii, Isao Fujita, Hideaki Miyaso, Tatsuya Toyokawa, Masaru Inagaki   +7 more
wiley   +1 more source

Factors Influencing Resection Time in Endoscopic Submucosal Dissection for Rectal Neuroendocrine Tumors

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives The usefulness of endoscopic submucosal dissection (ESD) for rectal neuroendocrine tumors (NETs) is well established. However, factors influencing resection time remain unclear. This study aimed to identify these factors during ESD for rectal NETs.
Shinya Nakatani, Junnosuke Hayasaka, Tsuyoshi ishii, Minoru Oda, Yusuke Kawai, Hiroshi Yamato, Yorinari Ochiai, Yugo Suzuki, Yutaka Mitsunaga, Hiroyuki Odagiri, Akira Matsui, Yasuro Miura, Shu Hoteya   +12 more
wiley   +1 more source

Comparison of Endoscopic Ultrasound‐guided Tissue Acquisition and Percutaneous Liver Biopsy for Diagnosing Focal Liver Lesions: A Retrospective Single‐Center Study

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background and Aim Accurate diagnosis of focal liver lesions (FLLs) is crucial for determining the appropriate treatment strategies. Although percutaneous liver biopsy (PLB) is the standard diagnostic procedure, it has limitations, particularly for difficult‐to‐access lesions.
Kei Yane, Keita Seto, Yuki Ikeda, Kotaro Morita, Mayu Shimizu, Koki Yoshida, Sota Hirokawa, Tetsuya Sumiyoshi, Michiaki Hirayama, Hitoshi Kondo   +9 more
wiley   +1 more source

Characterization of the neuroendocrine pancreatic tumors nature by MDCT enhancement pattern: a radio-pathological correlation [PDF]

, 2012
Introduction Pre-operative suspicion of neuroendocrine pancreatic lesions nature arises both from clinical (presence and the type of secreted hormone) and imaging findings.
NOVARIA, LISA
core  

KRAS‐G12C: The neglected biomarker to detect patients with MUTYH‐associated polyposis

International Journal of Cancer, Volume 158, Issue 6, Page 1588-1598, 15 March 2026.
What's new? MUTYH‐associated polyposis is an underdiagnosed recessive syndrome that predisposes individual to colorectal cancer and frequently displays KRAS‐G12C mutations. By analyzing a large cohort of colorectal cancer patients routinely tested for KRAS, the authors assessed whether KRAS‐G12C detection could serve as a pre‐screening tool for the ...
Ana Beatriz Deleame Medeiros, Gabriel Oliveira dos Santos, José Claudio Casali‐da‐Rocha, Samuel Aguiar Junior, Virgilio Souza e Silva, Gustavo Nóriz Berardinelli, Augusto Perazzolo Antoniazzi, Rui Manuel Reis, Dirce Maria Carraro, Giovana Tardin Torrezan   +9 more
wiley   +1 more source

Extent and Incidence of Pseudo‐Worsening of Kidney Function Due to Oral Antitumor Therapeutics in the AMBORA Cohort: An Analysis of Real‐World Data

Clinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 802-811, March 2026.
A considerable number of oral antitumor therapeutics (OAT) has the potential for causing pseudo‐worsening of kidney function (PW) due to inhibition of renal creatinine secretion, i.e., kidney function is unaffected, while creatinine‐based calculation of glomerular filtration rate (eGFR) erroneously indicates an impaired kidney function.
Michael I. Sponfeldner, Pauline Dürr, Phyllis Lensker, Katja Gessner, Lisa Cuba, Rainer Fietkau, Markus F. Neurath, Bernd Wullich, Marianne Pavel, Carola Berking, Matthias W. Beckmann, Andreas Mackensen, Frank Dörje, Martin F. Fromm   +13 more
wiley   +1 more source

Increased incidence, survival, and registration quality of primary hepato‐pancreato‐biliary cancers in the Netherlands Cancer Registry

International Journal of Cancer, Volume 158, Issue 5, Page 1237-1249, 1 March 2026.
What's New? Primary hepato‐pancreato‐biliary cancers have poor prognosis and their reporting often scores low on standard data quality indicators in population‐based cancer registries. This comprehensive evaluation of cases in the Netherlands Cancer Registry shows that both the incidence and survival rates of most primary hepato‐pancreato‐biliary ...
Lydia G. van der Geest, Marianne van der Mark, Joanne Verheij, Arantza Farina Sarasqueta, Judith de Vos‐Geelen, Marc G. Besselink, Vincent E. de Meijer, Ignace H. J. T. de Hingh, Bert A. Bonsing, Philip R. de Reuver, Francois E. J. A. Willemssen, Pauline A. J. Vissers, Otto Visser, the Dutch Pancreatic Cancer Group and the Dutch Hepatocellular & Cholangiocarcinoma Group   +13 more
wiley   +1 more source

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. [PDF]

, 1990
Extracts from BSC-40 cells infected with vaccinia recombinants expressing either the yeast KEX2 prohormone endoprotease or a human structural homologue (fur gene product) contained an elevated level of a membrane-associated endoproteolytic activity that ...
Barr, P, Brake, A, Bresnahan, P, Gibson, H, Leduc, R, Thomas, G, Thomas, L, THORNER, Jeremy W.   +7 more
core   +1 more source