Results 41 to 50 of about 7,573,905 (257)

Reduction of degrees of Freedom in three-dimensional ANCF beam of 24-DOF beam element by component mode synthesis

open access: yesNihon Kikai Gakkai ronbunshu, 2014
This paper describes how to reduce degrees of freedom for the absolute nodal coordinate formulation (ANCF) of three-dimensional beam made up of 24 degrees of freedom beam elements by applying the component mode synthesis. The stiffness matrix of the ANCF
Kosuke KADOKURA, Nobuyuki KOBAYASHI
doaj   +1 more source

Analysis on deformation and failure of Jijianao ventilation shaft roadway and supporting countermeasures

open access: yesMeikuang Anquan, 2021
In order to solve the problem of large deformation of Jijianao ventilation shaft roadway in Xinyuan Mine, the nature of the surrounding rock of the ventilation shaft roadway was studied. The deformation and failure mode of the roadway was systematically
YANG Yong
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Understanding creep in sandstone reservoirs – theoretical deformation mechanism maps for pressure solution in granular materials [PDF]

open access: yes, 2014
Subsurface exploitation of the Earth’s natural resources removes the natural system from its chemical and physical equilibrium. As such, groundwater extraction and hydrocarbon production from subsurface reservoirs frequently causes surface subsidence and
Hangx, Suzanne   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Deformation of fine-grained synthetic peridotite under wet conditions [PDF]

open access: yes, 1997
Fine-grained hydrated peridotite mylonites have been proposed to play an important role in controlling the strength of the continental lithosphere during rifting.
McDonnell, R.D.   +2 more
core   +1 more source

Heterogeneous subgreenschist deformation in an exhumed sediment‐poor mélange [PDF]

open access: yes, 2022
Many described subduction complexes (or mélanges) exhumed from seismogenic depths comprise thick, turbidite‐dominated sequences with deformed zones containing clasts or boudins of more competent sandstone and/or basalt.
Buchs, D.   +13 more
core   +2 more sources

Investigation of Reasonable Reserved Deformation of Deep-Buried Tunnel Excavation Based on Large Deformation Characteristics in Soft Rock

open access: yesBuildings
This study studies the deformation characteristics of the diversion tunnel of Jinping II Hydropower Station in order to guarantee the safety of the excavation of a large-section soft rock tunnel with a depth of 1000 m and increased ground stress.
Zhen Yang   +4 more
doaj   +1 more source

Numerical simulation of Rayleigh wave-induced large lateral spreading deformation in gentle sloping ground using SPH

open access: yesYantu gongcheng xuebao, 2023
The sloping ground may suffer from lateral spreading due to earthquake-induced soil softening or liquefaction, and this deformation is usually relatively limited in the gentle sloping ground.
LI Yunyi , WANG Rui , ZHANG Jianmin
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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