Results 51 to 60 of about 280,675 (318)

A Concise and Geometrically Exact Planar Beam Model for Arbitrarily Large Elastic Deformation Dynamics

open access: yesFrontiers in Robotics and AI, 2021
The potential of large elastic deformations in control applications, e.g., robotic manipulation, is not yet fully exploited, especially in dynamic contexts.
Gerold Huber, Dirk Wollherr, Martin Buss
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Large deformation plasticity

open access: yesActa Mechanica Sinica, 2020
AbstractThe theory of plasticity as a special field of continuum mechanics deals with the irreversible, i.e. permanent, deformation of solids. Under the action of given loads or deformations, the state of the stresses and strains or the strain rates in these bodies is described.
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Permeability evolution during progressive development of deformation bands in porous sandstones [PDF]

open access: yes, 2003
Triaxial deformation experiments were carried out on large (0.1 m) diameter cores of a porous sandstone in order to investigate the evolution of bulk sample permeability as a function of axial strain and effective confining pressure. The log permeability
Kwon, O.   +7 more
core   +1 more source

Numerical simulation on resistance of flexible pipe to radial compression

open access: yesYou-qi chuyun, 2020
Flexible pipes are usually clamped by tensioners and other installation tools during installation.Too small clamping force may lead to the peeling of the oversheath of the pipe, while too large clamping force will lead to radial compression damage of the
Bo GAO   +5 more
doaj   +1 more source

Analytical and Numerical Solutions for Three-Dimensional Granular Collapses

open access: yesGeosciences, 2023
This research paper presents a comprehensive approach to investigating dry granular collapses in three dimensions, by combining analytical, numerical, and experimental methods.
Emmanuel Wyser   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Reduction of system matrices of plate in absolute nodal coordinate formulation by component mode synthesis method

open access: yesNihon Kikai Gakkai ronbunshu, 2014
In this paper, we present a reduction method of the system matrix of a flexible thin plate element of 48 degrees of freedom, which is formulated on the basis of the absolute nodal coordinate method (ANCF) by use of the component mode synthesis method. We
Yuya OKAZAWA   +2 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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