Results 51 to 60 of about 1,036,303 (287)

Spontaneous avalanche dephasing in large Rydberg ensembles

Physical Review A, 2017
Strong dipole-exchange interactions due to spontaneously produced contaminant states can trigger rapid dephasing in many-body Rydberg ensembles [E. Goldschmidt et al., PRL 116, 113001 (2016)]. Such broadening has serious implications for many proposals to coherently use Rydberg interactions, particularly Rydberg dressing proposals. The dephasing arises
Boulier, T., Magnan, E., Bracamontes, C., Maslek, J., Goldschmidt, E. A., Young, J. T., Gorshkov, A. V., Rolston, S. L., Porto, J. V.   +8 more
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Kinetic Methods for Inverse Problems

, 2018
The Ensemble Kalman Filter method can be used as an iterative numerical scheme for parameter identification or nonlinear filtering problems. We study the limit of infinitely large ensemble size and derive the corresponding mean-field limit of the ...
Herty, Michael, Visconti, Giuseppe
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Ensemble climate-impact modelling: extreme impacts from moderate meteorological conditions

Environmental Research Letters, 2020
The investigation of risk due to weather and climate events is an example of policy relevant science. Risk is the result of complex interactions between the physical environment (geophysical events or conditions, including but not limited to weather and ...
Karin van der Wiel, Frank M Selten, Richard Bintanja, Russell Blackport, James A Screen   +4 more
doaj   +1 more source

Resilience for large ensemble computations

, 2023
With the increasing power of supercomputers, ever more detailed models of physical systems can be simulated, and ever larger problem sizes can be considered for any kind of numerical system. During the last twenty years the performance of the fastest clusters went from the teraFLOPS domain (ASCI RED: 2.3 teraFLOPS) to the pre-exaFLOPS domain (Fugaku ...
openaire   +4 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Skilful interannual climate prediction from two large initialised model ensembles

Environmental Research Letters, 2020
Climate prediction skill on the interannual timescale, which sits between that of seasonal and decadal, is investigated using large ensembles from the Met Office and CESM initialised coupled prediction systems.
Nick Dunstone, Doug Smith, Steve Yeager, Gokhan Danabasoglu, Paul-Arthur Monerie, Leon Hermanson, Rosie Eade, Sarah Ineson, Jon Robson, Adam Scaife, Hong-Li Ren   +10 more
doaj   +1 more source

Ensemble averageability in network spectra

, 2007
The extreme eigenvalues of connectivity matrices govern the influence of the network structure on a number of network dynamical processes. A fundamental open question is whether the eigenvalues of large networks are well represented by ensemble averages.
Adilson E. Motter, Dong-Hee Kim, E. Gumbel, L. M. Pecora, S. Redner, T. Kato, Y. Wang   +6 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source