Results 71 to 80 of about 85,058 (265)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Analysis of inflationary models in higher-dimensional uniform inflation
Journal of High Energy PhysicsWe consider higher-dimensional uniform inflation, in which the extra dimensions expand at the same rate as three-dimensional non-compact space during inflation.
Takuya Hirose
doaj +1 more source
Black hole evaporation and large extra dimensions [PDF]
Physics Letters B, 2000 LaTeX with elsart.sty, 10 pages, 1 EPS figure. Replaced with final version to appear in Phys.
Casadio R., Harms B.
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Interpreting the 3 TeV WH resonance as a W′ boson
Journal of High Energy Physics, 2017 Motivated by a local 3.2 − 3.4 sigma resonance in WH and ZH in the ATLAS Run 2 data, we attempt to interpret the excess in terms of a W′ boson in a SU(2)1 × SU(2)2×U(1)X model. We stretch the deviation from the alignment limit of the Equivalence Theorem,
Kingman Cheung +3 more
doaj +1 more source
A new mechanism for symmetry breaking from nilmanifolds
Journal of High Energy Physics, 2020 We present a method to obtain a scalar potential at tree level from a pure gauge theory on nilmanifolds, a class of negatively-curved compact spaces, and discuss the spontaneous symmetry breaking mechanism induced in the residual Minkowski space after ...
David Andriot +4 more
doaj +1 more source
Kinetic mixing, dark photons and extra dimensions. Part III. Brane localized dark matter
Journal of High Energy Physics, 2021 Extra dimensions have proven to be a very useful tool in constructing new physics models. In earlier work, we began investigating toy models for the 5-D analog of the kinetic mixing/vector portal scenario where the interactions of dark matter, taken to ...
Thomas G. Rizzo, George N. Wojcik
doaj +1 more source
Affleck-Dine baryogenesis in large extra dimensions [PDF]
Physical Review D, 2002 4 pages, LaTeX file, no figures. Important improvements on the paper. Conclusions unchanged.
Mazumdar, Anupam, Pérez-Lorenzana, A.
openaire +3 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source