Results 81 to 90 of about 91,637 (344)
Journal of High Energy Physics, 2022 Supergravity brane solutions allow for a generalised type of Kaluza-Klein reduction onto brane worldvolumes. The known replacement of a flat worldvolume metric by a Ricci-flat metric constitutes a consistent Kaluza-Klein truncation of the starting higher-
Rahim Leung, K.S. Stelle
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Holographic self-tuning of the cosmological constant
Journal of High Energy Physics, 2017 We propose a brane-world setup based on gauge/gravity duality in which the four-dimensional cosmological constant is set to zero by a dynamical self-adjustment mechanism. The bulk contains Einstein gravity and a scalar field. We study holographic RG flow
Christos Charmousis +2 more
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
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Non-trivial thick brane realisations with 3-forms
Journal of High Energy PhysicsWe explore the construction of four-dimensional thick branes supported by massless 3-forms in a five-dimensional bulk space. The required residual Poincaré symmetry on the brane is realised as a combination of the bulk symmetries and the internal gauge ...
Bruno J. Barros, Jose Beltrán Jiménez
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FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Searching for a dark dimension right-handed neutrino in KATRIN
Journal of High Energy PhysicsWe study the possibility that the Right-handed neutrino is a five-dimensional state propagating along a micron size extra dimension, as required in the dark dimension proposal.
Ignatios Antoniadis +2 more
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Collapse of Large Extra Dimensions [PDF]
Physical Review D, 2001 In models of spacetime that are the product of a four-dimensional spacetime with an ``extra'' dimension, there is the possibility that the extra dimension will collapse to zero size, forming a singularity. We ask whether this collapse is likely to destroy the spacetime.
openaire +3 more sources
Gravitational echoes from braneworlds
Journal of High Energy PhysicsGravitational echoes can be used to probe the structure of spacetime. In this paper, we investigate the gravitational echoes in different braneworld models in five-dimensional spacetime. We derive the gravitational perturbation equations of these models,
Chun-Chun Zhu +3 more
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