Results 171 to 180 of about 257,227 (292)

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

British Journal of Clinical Pharmacology, EarlyView.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf, Ymke van der Velde, Paul R. V. Malik, Jelmer R. Prins, Sanne J. Gordijn, Daan J. Touw, Paola Mian   +6 more
wiley   +1 more source

History of large-for-gestational-age birth is independently associated with subsequent gestational diabetes in Chinese multiparous women: a retrospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Yang J, Zhong S, Wang M, Liu Y, Wang Y, Deng Y, Ma K, Yang A, Li Y, Xu C.   +9 more
europepmc   +1 more source

Weight gain patterns among pregnancies with obesity and small- and large-for-gestational-age births. [PDF]

Obesity (Silver Spring), 2023
Petersen JM, Hutcheon JA, Bodnar LM, Parker SE, Ahrens KA, Werler MM.   +5 more
europepmc   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Prevalence of Cardiovascular Functional Anomalies in Large-for-Gestational-Age (LGA) Fetuses by Fetal Echocardiography. [PDF]

J Clin Med
Biały ŁH, Sylwestrzak O, Murlewska J, Sokołowski Ł, Strzelecka I, Respondek-Liberska M.   +5 more
europepmc   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

Born Large for Gestational Age: Bigger Is Not Always Better [PDF]

The Journal of Pediatrics, 2016
Valentina Chiavaroli, José G.B. Derraik, Paul L. Hofman, Wayne S. Cutfield   +3 more
openaire   +2 more sources

Ponderal Index Increases With Maternal Glucose, but Large for Gestational Age Better Predicts Infant Morbidity in Type 1 Diabetes Pregnancies. [PDF]

Acta Paediatr
Barikan J, Hagman A, Bohlin L, Elfvin A, Linden K, Dotevall A, Ögge LE.   +6 more
europepmc   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

Prevalence of Large-for-Gestational Age and Macrosomia Among Livebirths in 23 Low- and Middle-Income Countries Between 2000 and 2021: An Individual Participant Data Analysis. [PDF]

BJOG
Kirakoya-Samadoulougou F, Ukwishaka J, Ngwasiri C, Subedi S, Hazel EA, Erchick DJ, Wu LSF, Grandi C, Lachat C, Toe LC, Roberfroid D, Huybregts L, Labrique AB, Rashid M, Shaikh S, Haque R, Baqui AH, Saha SK, Khanam R, Rahman S, Silveira MMF, Buffarini R, Shapiro RL, Zash R, Zhu Z, Zeng L, Qiu X, He J, Gebreyesus SH, Tesfamariam K, Chan G, Bekele D, Adu-Afarwuah S, Dewey KG, Gyaase S, Wylie BJ, Taneja S, Chowdhury R, Babu GR, Deepa R, Rishard M, Lazzerini M, Rodriguez-Sibaja MJ, Acevedo-Gallegos S, Ashorn P, Maleta K, Mullany LC, Jehan F, Ilyas M, Rogerson SJ, Unger HW, Ghosh R, Musange S, Mongkolchati A, Keentupthai P, Fawzi W, Wang D, Schmiegelow C, Minja D, Hjort L, Lusingu JPA, Smith ER, Masanja H, Kabole FM, Slim SN, Kakuru A, Kajubi R, Walker D, Waiswa P, Ramokolo V, Zembe-Mkabile W, Semrau K, Hamer DH, Chico RM, Chaponda EB, Manasyan A, Pry JM, Musokotwane K, Banda B, Prendergast A, Chasekwa B, Katz J, Lee ACC, Black RE, Subnational Collaborative Group for Vulnerable Newborn Prevalence.   +84 more
europepmc   +1 more source