Results 141 to 150 of about 367,099 (262)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Intestinal IL-22RA1 signaling regulates <i>Chlamydia</i> deficient in plasmid-encoded pGP3 spreading to large intestine. [PDF]

Front Microbiol
Tian Q, Fang G, Ma J, Wang L, Zuo Z, Zhang T.   +5 more
europepmc   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Perforation of the Large Intestine by a Fish Bone Mimicking Cancer: A Rare Case Report. [PDF]

Cureus
Herrera Hernández D, Barragán Jiménez EM, Cano Cabrera P, Flores García PP, Paternina Gonzalez IY, Páramo Hernández DL, Burciaga Castañeda R, Treviño Flores JC.   +7 more
europepmc   +1 more source

Cancer in a polyp of the large intestine - an interdisciplinary decision problem. [PDF]

Prz Gastroenterol, 2021
Stefaniak P, Majewska H, Zadrożny D, Godlewski J.   +3 more
europepmc   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Investigating microbial population structure and function in the chicken caeca and large intestine over time using metagenomics. [PDF]

BMC Res Notes
Star-Shirko B, Pangga GM, McKenna A, Corcionivoschi N, Richmond A, Ijaz UZ, Gundogdu O.   +6 more
europepmc   +1 more source

Histological study on regional specificity of the mucosal nerve network in the rat large intestine. [PDF]

J Vet Med Sci, 2023
Nakanishi S, Mantani Y, Ohno N, Morishita R, Yokoyama T, Hoshi N.   +5 more
europepmc   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Severity of Brachyspira hyodysenteriae colitis correlates to the changes observed in the microbiota composition and its associated functionality in the large intestine. [PDF]

Anim Microbiome
Pérez-Pérez L, Galisteo C, Sanjuán JMO, Cobo-Díaz JF, Puente H, Rubio P, Carvajal A, Arguello H.   +7 more
europepmc   +1 more source