Optical Mode Calculation in Large-Area Photonic Crystal Surface-Emitting Lasers
We discuss algorithms and numerical challenges in constructing and resolving spectral problems for photonic crystal surface-emitting lasers (PCSELs) with photonic crystal layers and large (up to several tens of mm$^{2}$) emission areas.
Mindaugas Radziunas +4 more
doaj +1 more source
Single-Mode Operation in Flat Fibers Slab Waveguide via Modal Leakage
An approach to obtain single-mode operation on a semirectangular large core area Flat Fiber (FF) slab waveguide is proposed. A new design of FF with two defect eye holes is presented, and its single-mode guiding is analyzed by simulation. To validate the
Soo Yong Poh +6 more
doaj +1 more source
Modeling and Analysis of MPTCP Proxy-based LTE-WLAN Path Aggregation
Long Term Evolution (LTE)-Wireless Local Area Network (WLAN) Path Aggregation (LWPA) based on Multi-path Transmission Control Protocol (MPTCP) has been under standardization procedure as a promising and cost-efficient solution to boost Downlink (DL) data
Chen, Bolin +4 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Advances in Silica-Based Large Mode Area and Polarization-Maintaining Photonic Crystal Fiber Research. [PDF]
Ma Y, Wan R, Li S, Yang L, Wang P.
europepmc +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Progress in Developing Hybrid RPCs: GEM-like Detectors with Resistive Electrodes
We have recently developed an innovative detector of photons and charged particles: a GEM-like gaseous amplification structure with resistive electrodes instead of commonly used metallic ones.
Agocs +13 more
core +1 more source

