Results 61 to 70 of about 219,084 (199)

On the Number of Mutually Disjoint Cyclic Designs and Large Sets of Designs

open access: yes, 2007
Let N(t; v; k; ) be the maximum possible number of mutually disjoint cyclic t- (v; k; ) designs. In this paper we find the number N(t; v; k; ) for two sets of parameters, and give bounds for other sets of parameters.
Spyros S. Magliveras, Iliya Bluskov
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Block Transitive Resolutions of t-designs and Room Rectangles

open access: yes, 1993
By a resolution of t-designs we mean a partition of the trivial design \Gamma X k \Delta of all k-subsets of a v-set X into t \Gamma (v 0 ; k; ) designs, where v 0 v.
Spyros S. Magliveras   +2 more
core  

Designs for an asymmetric gradient set and a compact superconducting magnet for neural magnetic resonance imaging

open access: yes, 1999
Imaging of the head and neck is the most commonly performed clinical magnetic resonance imaging (MRI) examination [R. G. Evans and J. R. G. Evans, AJR 157, 603 (1991)].
Hinds, G. W.   +9 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Some new large sets of geometric designs of type ${LS[3][2,3,2^8]}$

open access: yes, 2016
Let $V$ be an $n$-dimensional vector space over $\F_q$. By a {\textit {geometric}} $t$-$[q^n,k,\lambda]$ design we mean a collection $\mathcal{D}$ of $k$-dimensional subspaces of $V$, called blocks, such that every $t$-dimensional subspace $T$ of $V ...
Magliveras, Spyros S.   +2 more
core  

Uniform hypergraphs containing no grids

open access: yes, 2013
A hypergraph is called an r×r grid if it is isomorphic to a pattern of r horizontal and r vertical lines, i.e.,a family of sets {A1, ..., Ar, B1, ..., Br} such that Ai∩Aj=Bi∩Bj=φ for 1 ...
Füredi, Zoltán, Ruszinkó, Miklós
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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