Results 91 to 100 of about 1,104,970 (268)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Periodic solutions for a second order nonlinear neutral functional differential equation with variable delay

open access: yesLe Matematiche, 2014
In this paper we study the existence of periodic solutions of the second order nonlinear neutral differential equation with functional delay. We invert the given equation to obtain an integral, but equivalent, equation from which we define a fixed point ...
Abdelouaheb Ardjouni, Ahcene Djoudi
doaj  

Enabling Intelligent Data Modeling with AI for Business Intelligence and Data Warehousing: A Data Vault Case Study

open access: yesSystems
This study explores the innovative application of Artificial Intelligence (AI) in transforming data engineering practices, with a specific focus on optimizing data modeling and data warehouse automation for Business Intelligence (BI) systems.
Andreea Vines   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Harnessing AI in School Counselling: Exploring the Potential of ChatGPT for Student Support

open access: yesEducational Process: International Journal
Background/purpose. This study explores the extent to which ChatGPT, an AI-powered large language model, can support school counseling services in addressing students’ academic, social, and emotional needs, considering student AI literacy and adoption.
Ahmad Al-shraifin   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Global solution with partial large initial data to the Keller–Segel–Navier–Stokes equations in Besov spaces

open access: yesJournal of Inequalities and Applications
In this paper, we prove a global large solution result to the Keller–Segel–Navier–Stokes equations in critical Besov spaces. The result indicates that the global solutions exist without any small conditions imposed on the initial oxygen concentration c 0
Xuhuan Zhou
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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